Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Acetaminophen plus Diphenhydramine vs placebo

Anaphylatic reactions ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydramine led to lower anaphylatic reactions ‐ not reported compared with placebo; GRADE not reported.

1 finding from 1 review

Acetaminophen plus Diphenhydrammine vs placebo (Unit of randomisation: transfusion)

Anaphylatic reactions ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydrammine led to lower anaphylatic reactions ‐ not reported compared with placebo (Unit of randomisation: transfusion); GRADE not reported.

1 finding from 1 review