Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Heart

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Ablation vs antiarrhythmic drug

Periprocedural complications and other safety outcomes · people with non‐paroxysmal atrial fibrillation

It is very uncertain whether ablation changes periprocedural complications and other safety outcomes compared with antiarrhythmic drug (very low certainty).

1 finding from 1 review

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation 2016 · Cochrane Headline outcomes only
RR 0.94 [0.16, 5.68]
3 studies · 261 participants
Very low

Ablation vs antiarrhythmic drug

Freedom from atrial arrhythmia · people with non‐paroxysmal atrial fibrillation

Ablation may leads to higher freedom from atrial arrhythmia compared with antiarrhythmic drug (low certainty).

1 finding from 1 review

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation 2016 · Cochrane Headline outcomes only
RR 1.84 [1.17, 2.88]
3 studies · 261 participants
Low

Ablation vs antiarrhythmic drug

Participants needing cardioversion · people with non‐paroxysmal atrial fibrillation

Ablation probably leads to lower participants needing cardioversion compared with antiarrhythmic drug (moderate certainty).

1 finding from 1 review

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation 2016 · Cochrane Headline outcomes only
RR 0.62 [0.47, 0.82]
3 studies · 261 participants
Moderate

Ablation vs antiarrhythmic drug

Cardiac hospitalisation Hospitalisations directly related to ablation or antiarrhythmic drugs · people with non‐paroxysmal atrial fibrillation

Ablation may leads to lower cardiac hospitalisation Hospitalisations directly related to… compared with antiarrhythmic drug (low certainty).

1 finding from 1 review

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation 2016 · Cochrane Headline outcomes only
RR 0.27 [0.1, 0.72]
2 studies · 216 participants
Low

Ablation vs antiarrhythmic drug

Significant bradycardia or need for a pacemaker · people with non‐paroxysmal atrial fibrillation

Ablation showed no clear difference in significant bradycardia or need for a pacemaker compared with antiarrhythmic drug (low certainty).

1 finding from 1 review

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation 2016 · Cochrane Headline outcomes only
RR 0.2 [0.02, 1.63]
3 studies · 261 participants
Low