ATRA in addition to chemotherapy vs chemotherapy alone
Toxicity: grade 3 or 4 nausea ± vomiting · adults with acute myeloid leukaemia (AML) (non‐acute promyelocytic leukaemia (APL))
It is very uncertain whether ATRA in addition to chemotherapy changes nausea/vomiting grade III/IV compared with chemotherapy only (very low certainty).
1 finding from 1 review
- Effects of all‐trans retinoic acid (ATRA) in addition to chemotherapy for adults with acute myeloid leukaemia (AML)… 2018 · Cochrane Headline outcomes onlyRR 1.46 [0.75, 2.85]2 studies · 337 participantsVery low