Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

All studies · patients with the initiation of oral anticoagulation

It is very uncertain whether 5 mg changes all studies compared with 10 mg (very low certainty).

1 finding from 1 review

Optimal loading dose of warfarin for the initiation of oral anticoagulation 2012 · Cochrane Headline outcomes only
RR 1.17 [0.77, 1.77]
4 studies · 352 participants
Very low

Single INR measure · patients with the initiation of oral anticoagulation

It is very uncertain whether 5 mg changes single INR measure compared with 10 mg (very low certainty).

1 finding from 1 review

Optimal loading dose of warfarin for the initiation of oral anticoagulation 2012 · Cochrane Headline outcomes only
RR 1.49 [1.01, 2.21]
2 studies · 250 participants
Very low

Consecutive INR measures · patients with the initiation of oral anticoagulation

It is very uncertain whether 5 mg changes consecutive INR measures compared with 10 mg (very low certainty).

1 finding from 1 review

Optimal loading dose of warfarin for the initiation of oral anticoagulation 2012 · Cochrane Headline outcomes only
RR 0.86 [0.62, 1.19]
2 studies · 102 participants
Very low