Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 1 · 33.3%

28 days on/off antibiotic regimen vs 28 days on/off placebo regimen

Serious adverse events · people with bronchiectasis

28 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 28 days on/off placebo regimen (low certainty).

1 finding from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
OR 1 [0.68, 1.46]
Studies not reported
Low

14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen

Serious adverse events · people with bronchiectasis

14 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 28 days on/off antibiotic regimen (moderate certainty).

1 finding from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
OR 0.83 [0.37, 1.86]
Studies not reported
Moderate

14 days on/off antibiotic regimen vs 14 days on/off placebo regimen

Serious adverse events · people with bronchiectasis

14 days on/off antibiotic regimen showed no clear difference in serious adverse events compared with 14 days on/off placebo regimen (high certainty).

1 finding from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
OR 0.92 [0.63, 1.33]
Studies not reported
High