What do systematic reviews say?

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel

The review found no eligible studies for this question.

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond (end of orthodontic treatment)
  Additional SoF Table 1. Number of participants with more severe DLs: none of the trials reported this outcome.
  0 studies
  No studies found

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond; mean follow-up 16.6 months
  Additional SoF Table 1. Adverse effects: with placebo gel 0.60%; with fluoride gel 0.00% (0 to 0); difference 0.60% fewer (0.60 fewer to 0.60 fewer); relative effect not estimable; 312 participants (1 RCT); certainty…
  1 study · 312 participants
  Very low

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel, professionally applied every 3 months plus home use vs Placebo gel

It is very uncertain whether 12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel,… changes number of participants with new demineralised lesions (DLs) compared with 0 ppm F placebo gel (very low certainty).

• Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes

  At debond; mean follow-up 16.6 months
  RR 0.99 [0.76, 1.27]
  1 study · 312 participants
  Very low