Question · asked by 1 review
12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel: Adverse effects
- Population
- Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
- Intervention
- 12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel
- Comparison
- Placebo gel
- Outcome
- Adverse effects
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs 0 ppm F placebo gel Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; mean follow-up 16.6 months Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane All outcomes | Additional SoF Table 1. Adverse effects: with placebo gel 0.60%; with fluoride gel 0.00% (0 to 0); difference 0.60% fewer (0.60 fewer to 0.60 fewer); relative effect not estimable; 312 participants (1 RCT); certainty… | 1 study · 312 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes | 1 February 2019 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.