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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

70 questions in 8 reviews · Temporomandibular disorders and sleep

current versions
No studies 70 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Occlusal splint vs Another occlusal splint with a different mechanism of action
Severity of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Muscle pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Muscle pain at rest · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Another occlusal splint with a different mechanism of action
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 3 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Severity of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Another occlusal splint with a different mechanism of action
Muscle pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 3 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs No treatment or placebo (non-occlusal or transparent-foil placebo splint)
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 1 as 'Not reported'; this outcome was not reported by any included study for this comparison. Discomfort was not reported in any included study across the whole review.0 studiesNo studies
Occlusal splint vs Another occlusal splint with a different mechanism of action
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Frequency of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Muscle pain at mastication · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Pharmacological therapy
Muscle pain at rest · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Frequency of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Muscle pain at rest · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs No treatment or placebo (non-occlusal or transparent-foil placebo splint)
Recurrence rate · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 1 as 'Not reported'; this outcome was not reported by any included study for this comparison. Recurrence rate was not reported in any included study across the whole review.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Severity of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Severity of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Acupuncture
Frequency of joint noise · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 3 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Another occlusal splint with a different mechanism of action
Discomfort · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Occlusal splint vs Another occlusal splint with a different mechanism of action
Muscle pain at rest · People with temporomandibular disorders (TMD)
Occlusal interventions for managing temporomandibular disorders (2024) · Cochrane
Listed in Summary of findings 2 as 'Not reported'; this outcome was not reported by any included study for this comparison.0 studiesNo studies
Cognitive behavioural therapy (CBT) vs Alternative (active) treatment (e.g. oral splint, medication, self-care or disease management)
Quality of life · People aged 12 years and over with painful TMD lasting 3 months or longer
Psychological therapies for temporomandibular disorders (TMDs) (2022) · Cochrane
This outcome was not measured (not synthesised for this comparison; review-wide only one study reported quality of life).NRNo studies
Cognitive behavioural therapy (CBT) vs Alternative (active) treatment (e.g. oral splint, medication, self-care or disease management)
Additional physical symptoms · People aged 12 years and over with painful TMD lasting 3 months or longer
Psychological therapies for temporomandibular disorders (TMDs) (2022) · Cochrane
This outcome was not measured (not synthesised for this comparison; review-wide only one study reported additional physical symptoms).NRNo studies
Cognitive behavioural therapy (CBT) vs Usual care, waiting list or no treatment (control)
Quality of life · People aged 12 years and over with painful TMD lasting 3 months or longer
Psychological therapies for temporomandibular disorders (TMDs) (2022) · Cochrane
This outcome was not measured for this comparison.NRNo studies
Cognitive behavioural therapy (CBT) vs Usual care, waiting list or no treatment (control)
Additional physical symptoms · People aged 12 years and over with painful TMD lasting 3 months or longer
Psychological therapies for temporomandibular disorders (TMDs) (2022) · Cochrane
This outcome was not measured for this comparison.NRNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Signs and symptoms of atypical swallowing and speech production disturbance · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Alteration of growth pattern (cephalometric data or facial analysis) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Change of the arch perimeter (plaster models) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Signs and symptoms of respiratory disease: mouth breathing, nasal airway resistance (clinical assessment/rhinomanometry/fibroscopy) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Reduction of upper airway resistance syndrome (UARS) and body-weight/BMI development (polysomnography) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Reduction of snoring (polysomnography) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Quality of life (validated scale) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Economic evaluation: costs · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Improvement of the overbite and overjet (plaster models) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Change of mandibular length (cephalometric data) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Educational outcomes: cognitive function (validated scale) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Improvement on sagittal relationship between the maxilla and mandible (cephalometric data) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Oral appliance or functional orthopaedic appliance vs Placebo or no treatment
Changes of the width between cuspids and first molars (plaster models) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children (2016) · Cochrane
The included study did not assess this outcome.0 studiesNo studies
Laser therapy
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
The review noted the noticeable absence of evidence for laser therapy; no eligible RCT evaluated it (Discussion).0 studiesNo studies
Reassurance / behavioral management (control of contributory factors)
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
The review noted the noticeable absence of evidence for reassurance among interventions for TMJ OA; no eligible RCT evaluated it (Discussion).0 studiesNo studies
Arthrocentesis
Outcome NR · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane
No study evaluated arthrocentesis for TMJ OA, which should be explored in future trials (Research recommendations Table 1).0 studiesNo studies