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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

601 questions in 75 reviews · Schizophrenia

current versions
No studies 601 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Collaborative care vs usual care
Personal recovery ‐ not reported · severe mental illness
Collaborative care approaches for people with severe mental illness (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collaborative care vs usual care
Experience of care/satisfaction ‐ not reported · severe mental illness
Collaborative care approaches for people with severe mental illness (2024) · Cochrane
no estimate extractedNRNo studies
Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care
Cognitive functioning: clinically important change ‐ not measured · people with acute schizophrenia
Magnetic seizure therapy for people with schizophrenia (2023) · Cochrane
no estimate extractedNRNo studies
Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care
Quality of life: clinically important change ‐ not measured · people with acute schizophrenia
Magnetic seizure therapy for people with schizophrenia (2023) · Cochrane
no estimate extractedNRNo studies
Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care
Social functioning: clinically important change ‐ not measured · people with acute schizophrenia
Magnetic seizure therapy for people with schizophrenia (2023) · Cochrane
no estimate extractedNRNo studies
Group cognitive behavioural therapy for psychosis vs standard care
Clinically important change, shown as improved – as defined by individual studies · people with schizophrenia
Cognitive behavioural therapy (group) for schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Group cognitive behavioural therapy for psychosis vs standard care
Relapse · people with schizophrenia
Cognitive behavioural therapy (group) for schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Group cognitive behavioural therapy for psychosis vs standard care
Days in hospital · people with schizophrenia
Cognitive behavioural therapy (group) for schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Group cognitive behavioural therapy for psychosis vs standard care
Quality of life: clinically important change – as defined by individual studies. · people with schizophrenia
Cognitive behavioural therapy (group) for schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Continuation vs reduction of polypharmacy
Quality of life: clinically important change ‐ not reported · people with schizophrenia
Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Continuation vs reduction of polypharmacy
Global state: relapse/exacerbations of psychosis ‐ not reported · people with schizophrenia
Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia (2022) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Quality of life: clinically‐important change in general quality of life ‐ as defined by individual studies (long‐term). · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Adverse effects/events: at least 1 adverse effect ‐ as defined by individual studies · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Cognitive functioning: clinically‐important change in cognitive functioning ‐ as defined by individual studies (long‐term). · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Social functioning: clinically‐important change in social functioning ‐ as defined by individual studies (long‐term). · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs active controls
Quality of life: clinically important change in general quality of life ‐ as defined by individual studies (long term). Â · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs active controls
Adverse effects/events: at least 1 adverse effect ‐ as defined by individual studies. · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs active controls
Cognitive functioning: clinically‐important change in cognitive functioning ‐ as defined by individual studies (long‐term). Â · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs active controls
Social functioning: clinically‐important change in social functioning ‐ as defined by individual studies (long‐term). · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Clinically‐important change in general mental state, as defined by individual studie · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
Humour‐based interventions vs standard care
Clinically‐important change in negative symptoms, as defined by individual studies · People with schizophrenia
Humour‐based interventions for people with schizophrenia (2021) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU (all short‐term)
Service Use: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Global State: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
STRUCTURAL GROUP THERAPY (SGT) + TAU vs HANDICRAFT GROUP (HC) + TAU (all short‐term)
Service Utilisation: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Global functioning: Clinically important change ‐ as defined by each of the studies · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Adverse effects: Clinically important adverse effect ‐ as defined by each of the studies · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Service use: Hospital admission for any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Leaving the study early: For any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Adverse events: Clinically important change · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)
Service use: Hospital admission · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Cognitive functioning: Attaining normal cognitive functioning ‐ Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Global functioning: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)
Adverse events: Not reported · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Adverse events: Clinically important effect · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU (all short‐term)
Service use: Hospital admission for any reason · Adolescents with psychosis
Psychological interventions for psychosis in adolescents (2020) · Cochrane
no estimate extractedNRNo studies
Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs standard care
Substance use: Alcohol ‐ average score (C‐DIS‐R computer program for Diagnostic Interview Schedule: average score) · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs standard care
Substance use: Drug ‐ average score C‐DIS‐R computer program for Diagnostic Interview Schedule: average score · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs standard care
Mental state: Average score Schizophrenia symptoms on C‐DIS‐R computer program for Diagnostic Interview Schedule: average score · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs standard care
Quality of life/life satisfaction: (Quality of Life Interview section, scale of 1 to 7) · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy vs standard care
Adverse event: Death · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy vs standard care
Substance use: Alcohol · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Cognitive behavioural therapy vs standard care
Quality of life/ life satisfaction · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Contingency management vs standard care
Adverse event: Death ‐ not measured · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies
Contingency management vs standard care
Substance use: Alcohol · people with both severe mental illness and substance misuse
Psychosocial interventions for people with both severe mental illness and substance misuse (2019) · Cochrane
no estimate extractedNRNo studies