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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

434 questions in 75 reviews · Metabolic and Endocrine Disorders

current versions
No studies 434 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Health‐related quality of life · participants living with overweight or obesity
Calcium supplementation for people with overweight or obesity (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause mortality · participants living with overweight or obesity
Calcium supplementation for people with overweight or obesity (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Morbidity · participants living with overweight or obesity
Calcium supplementation for people with overweight or obesity (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs placebo
Sexual quality of life · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs placebo
Cardiovascular mortality · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs placebo
Prostate‐related events · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs placebo
Lower urinary tract symptoms · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs PDE5I
Cardiovascular mortality · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs PDE5I
Treatment withdrawal due to adverse events · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone vs PDE5I
Lower urinary tract symptoms · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone as an add‐on to PDE5I vs PDE5I alone
Cardiovascular mortality · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Testosterone as an add‐on to PDE5I vs PDE5I alone
Lower urinary tract symptoms · men with sexual dysfunction
Testosterone replacement in men with sexual dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs pharmacological therapy alone
Disease‐related complications · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs preoperative pharmacological therapy and surgery
All‐cause mortality · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs preoperative pharmacological therapy and surgery
Health‐related quality of life · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs pharmacological therapy alone
Disease recurrence · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs pharmacological therapy alone
All‐cause mortality · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs pharmacological therapy alone
Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Surgery alone vs pharmacological therapy alone
Non‐surgical therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas
Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane
no estimate extractedNRNo studies
Low glycaemic index (GI) or low glycaemic load (GL) diets vs any other diet
All‐cause mortality · people with obesity or overweight
Low glycaemic index or low glycaemic load diets for people with overweight or obesity (2023) · Cochrane
no estimate extractedNRNo studies
Low glycaemic index (GI) or glycaemic load (GL) diets vs higher GI or GL diets
All‐cause mortality · people with overweight or obesity
Low glycaemic index or low glycaemic load diets for people with overweight or obesity (2023) · Cochrane
no estimate extractedNRNo studies
Low glycaemic index (GI) or low glycaemic load (GL) diets vs any other diet
Health‐related quality of life · people with obesity or overweight
Low glycaemic index or low glycaemic load diets for people with overweight or obesity (2023) · Cochrane
no estimate extractedNRNo studies
Meglitinides vs sulphonylureas
Adverse events other than hypoglycaemia
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Meglitinides vs sulphonylureas
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Meglitinides vs sulphonylureas
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
SGLT‐2 inhibitors vs sulphonylureas
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
SGLT‐2 inhibitors vs sulphonylureas
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
SGLT‐2 inhibitors vs sulphonylureas
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
DPP‐4 inhibitors vs sulphonylureas
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
GLP‐1 analogues inhibitors vs sulphonylureas
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
GLP‐1 analogues inhibitors vs sulphonylureas
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Insulin analogues vs biphasic insulin
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Insulin analogues vs biphasic insulin
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Telemedicine vs usual care
Adverse events other than hypoglycaemia
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Telemedicine vs usual care
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Telemedicine vs usual care
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Patient education vs usual care
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Patient education vs usual care
Adverse events other than hypoglycaemia
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Patient education vs usual care
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Patient education vs usual care
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Drug dosage reduction vs usual care
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Drug dosage reduction vs usual care
All‐cause mortality
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Drug dosage reduction vs usual care
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Drug dosage reduction vs usual care
HbA1c (%)
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
DPP‐4 inhibitors vs sulphonylureas
Treatment satisfaction
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
DPP‐4 inhibitors vs sulphonylureas
Self‐care
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Meglitinides vs sulphonylureas
Health‐related quality of life
Interventions for people with type 2 diabetes mellitus fasting during Ramadan (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class I vs Normal Weight or Non‐Obese
OutcomesTime frame of absolute effects · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
Severe COVID · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies
Obesity Class II vs Normal Weight or Non‐Obese
Pneumonia · Adults with COVID‐19
Obesity as an independent risk factor for COVID‐19 severity and mortality (2023) · Cochrane
no estimate extractedNRNo studies