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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

141 questions in 31 reviews · Emergency and Critical Care

current versions
No studies 141 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Oxygenation vs no oxygenation during the apnoeic period preceding intubation
Hospital stay · people requiring tracheal intubation
Oxygenation during the apnoeic phase preceding intubation in adults in prehospital, emergency department,… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcomes, Time point of assessment · relatives, patients, and healthcare professionals during resucitation
Family presence during resuscitation (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
 · relatives, patients, and healthcare professionals during resucitation
Family presence during resuscitation (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
WHO progression score (level 7 or above) D28 ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
All‐cause mortality D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Olokizumab vs standard care/placebo
Adverse events ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Siltuximab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Siltuximab vs standard care/placebo
Adverse events ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Levilimab vs standard care/placebo
Clinical improvement D60 or more ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Levilimab vs standard care/placebo
WHO progression score (level 7 or above) D28 ‐ not reported · people with mild/moderate/severe/critical COVID‐19
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulants vs no treatment
Mortality related to COVID‐19 · people hospitalised with COVID‐19
Anticoagulants for people hospitalised with COVID‐19: a rapid review (2022) · Cochrane
no estimate extractedNRNo studies
Anticoagulants vs no treatment
Adverse events (minor bleeding) · people hospitalised with COVID‐19
Anticoagulants for people hospitalised with COVID‐19: a rapid review (2022) · Cochrane
no estimate extractedNRNo studies
Higher‐dose anticoagulants vs lower‐dose anticoagulants
Mortality related to COVID‐19 · people hospitalised with COVID‐19
Anticoagulants for people hospitalised with COVID‐19: a rapid review (2022) · Cochrane
no estimate extractedNRNo studies
Anticoagulants vs no treatment
Necessity for additional respiratory support · people hospitalised with COVID‐19
Anticoagulants for people hospitalised with COVID‐19: a rapid review (2022) · Cochrane
no estimate extractedNRNo studies
Canakinumab vs standard care/placebo
Clinical improvement D60 or above
Interleukin‐1 blocking agents for treating COVID‐19 (2022) · Cochrane
no estimate extractedNRNo studies
Canakinumab vs standard care/placebo
WHO Clinical Progression Score of level 7 or above D60 or above
Interleukin‐1 blocking agents for treating COVID‐19 (2022) · Cochrane
no estimate extractedNRNo studies
BNT162b2 – Pfizer/BioNTech + Fosun Pharma vs placebo
Confirmed SARS‐CoV‐2 infectionÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo
Systemic reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo
Any adverse event
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo
Serious adverse events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
FINLAY‐FR‐2 – Instituto Finlay de Vacunas vs placebo
Local reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Heterologous vaccination scheme vs homologous vaccination scheme
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Heterologous vaccination scheme vs homologous vaccination scheme
Confirmed symptomatic COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Heterologous vaccination scheme vs homologous vaccination scheme
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Heterologous vaccination scheme vs homologous vaccination scheme
All‐cause mortalityÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Booster vs placebo/no booster
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Booster vs placebo/no booster
Confirmed symptomatic COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Booster vs placebo/no booster
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Booster vs placebo/no booster
Any adverse event
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Booster vs placebo/no booster
Serious adverse events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
CVnCoV – CureVac AG vs placebo
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
ChAdOx1 – AstraZeneca + University of Oxford vs placebo
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
SII‐ChAdOx1 – Serum Institute of India/AstraZeneca + University of Oxford vs ChAdOx1 – University of Oxford
Confirmed SARS‐CoV‐2 infectionÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
SII‐ChAdOx1 – Serum Institute of India/AstraZeneca + University of Oxford vs ChAdOx1 – University of Oxford
Confirmed symptomatic COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
SII‐ChAdOx1 – Serum Institute of India/AstraZeneca + University of Oxford vs ChAdOx1 – University of Oxford
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
SII‐ChAdOx1 – Serum Institute of India/AstraZeneca + University of Oxford vs ChAdOx1 – University of Oxford
All‐cause mortalityÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
AD26.COV2.S – Janssen Pharmaceutical Companies vs placebo
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Gam‐COVID‐VAC – Sputnik V vs placebo
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
BNT162b2 – Pfizer/BioNTech + Fosun Pharma vs placebo
Systemic reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Gam‐COVID‐VAC – Sputnik V vs placebo
Systemic reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Gam‐COVID‐VAC – Sputnik V vs placebo
Any adverse event
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
Gam‐COVID‐VAC – Sputnik V vs placebo
Local reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
CoronaVac – Sinovac vs placebo
Confirmed SARS‐CoV‐2 infectionÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
WIBP‐CorV – Sinopharm‐Wuhan vs placebo
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
WIBP‐CorV – Sinopharm‐Wuhan vs placebo
All‐cause mortalityÂ
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
BBIBP‐CorV – Sinopharm‐Beijing vs placebo
Severe or critical COVID‐19
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
BBIBP‐CorV – Sinopharm‐Beijing vs placebo
All‐cause mortality
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
BNT162b2 – Pfizer/BioNTech + Fosun Pharma vs placebo
Local reactogenicity events
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies
NVX‐CoV2373 – Novavax vs placebo
Confirmed SARS‐CoV‐2 infection
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane
no estimate extractedNRNo studies