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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

240 questions in 36 reviews · Dementia and Cognitive Improvement

current versions
No studies 240 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Transcranial direct current stimulation (tDCS) vs sham tDCS
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Transcranial direct current stimulation (tDCS) vs sham tDCS
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Transcranial direct current stimulation (tDCS) vs sham tDCS
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Serious adverse events related to the use of physical restraints ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Duration of physical restraint use ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Fall‐related injuries ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Residents with at least one psychotropic medication ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Simple educational intervention vs usual care
Serious adverse events ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Social activities vs usual care
Consolidated sleep ‐ not measured · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Social activities vs usual care
Total wake time at night (minutes) ‐ not reported · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Social activities vs usual care
Number of nocturnal awakenings ‐ not reported · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Light therapy vs usual care
Consolidated sleep ‐ not measured · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Social activities vs usual care
Sleep onset latency ‐ not reported · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Carer interventions vs usual care
Consolidated sleep ‐ not measured · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Carer interventions vs usual care
Number of nocturnal awakenings ‐ not reported · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Carer interventions vs usual care
Sleep onset latency ‐ not reported · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Multimodal interventions vs usual care
Consolidated sleep ‐ not measured · sleep disturbances in dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Multimodal interventions vs usual care
Sleep onset latency ‐ not reported · sleep disturbances in dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Physical activities vs usual care
Consolidated sleep ‐ not measured · sleep disturbances in people with dementia
Non‐pharmacological interventions for sleep disturbances in people with dementia (2023) · Cochrane
no estimate extractedNRNo studies
Supportive and counselling interventions vs treatment
Depression remission post‐treatment · depression and anxiety for people with dementia
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment (2022) · Cochrane
no estimate extractedNRNo studies
Antiplatelet therapy vs placebo
Major bleeding (intracranial and extracranial) · s for prevention of cognitive decline and dementia in people with cerebral small vessel disease and no dementia
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Dual antiplatelet therapy vs single antiplatelet therapy
Incident dementia · people with cerebral small vessel disease and no dementia
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Dual antiplatelet therapy vs single antiplatelet therapy
Functional ability · people with cerebral small vessel disease and no dementia
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Antiplatelet drug vs placebo
Incident dementia · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in…
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Dual antiplatelet therapy vs single antiplatelet therapy
Any adverse events (excluding major bleeding) · people with cerebral small vessel disease and no dementia
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Antiplatelet therapy vs placebo
Incident dementia · s for prevention of cognitive decline and dementia in people with cerebral small vessel disease and no dementia
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but… (2022) · Cochrane
no estimate extractedNRNo studies
Complex information, support and training interventions vs information provision only
Use of health and social resources ‐ not reported · Informal caregivers of people with dementia
Remotely delivered information, training and support for informal caregivers of people with dementia (2021) · Cochrane
no estimate extractedNRNo studies
Advance care planning vs usual care
Pain ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Advance care planning vs usual care
Palliative care plan in place ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Advance care planning vs usual care
Quality of Life ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Organisation and delivery vs usual care
Pain ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Organisation and delivery vs usual care
Concordance with goals of care ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Advance care planning vs usual care
Comfort in dying ‐ not measured · advanced dementia
Palliative care interventions in advanced dementia (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcomes No of participants (studies)
Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
New diagnosis of dementia (at any time point after randomisation) Not measured
Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients (2021) · Cochrane
no estimate extractedNRNo studies
Nasogastric tubes vs no enteral tube feeding
Pressure ulcers · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
Nasogastric tubes vs no enteral tube feeding
Pain and comfort · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of Life · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
PEG vs no enteral tube feeding
Quality of life · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
PEG vs no enteral tube feeding
Pain and comfort · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
PEG vs no enteral tube feeding
Improvement of nutritional status · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies
Nasogastric tubes vs no enteral tube feeding
Survival time · people with severe dementia
Enteral tube feeding for people with severe dementia (2021) · Cochrane
no estimate extractedNRNo studies