Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

651 questions in 62 reviews · Wounds

current versions
No studies 651 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Skin substitute vs topical antimicrobial agent
Outcomes ( · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Skin substitute vs topical antimicrobial agent
Time to complete wound healing · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Skin substitute vs topical antimicrobial agent
Proportion of wounds completely healed · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Miscellaneous treatment vs miscellaneous treatment
Outcomes ( · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Topical antimicrobial agent vs topical non‐antimicrobial agent
Change in wound surface area over time or partial healing – not measured
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Topical antimicrobial vs alternative antimicrobial agent
Outcomes ( · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Topical antimicrobial vs alternative antimicrobial agent
Time to complete wound healing · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
Topical antimicrobial vs alternative antimicrobial agent
Proportion of wounds completely healed · people with facial burns
Topical treatment for facial burns (2020) · Cochrane
no estimate extractedNRNo studies
30° 3‐hourly tilt vs 90° tilt
Patient satisfaction · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
30° 3‐hourly tilt vs 90° tilt
Costs · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
2‐hourly repositioning vs 4‐hourly repositioning
Health‐related quality of life · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
2‐hourly repositioning vs 4‐hourly repositioning
Procedural pain · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
2‐hourly repositioning vs 4‐hourly repositioning
Patient satisfaction · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
2‐hourly repositioning vs 4‐hourly repositioning
Incremental costs · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
30° 3‐hourly tilt vs 90° tilt
Health‐related quality of life · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
30° 3‐hourly tilt vs 90° tilt
Procedural pain · adults
Repositioning for pressure injury prevention in adults (2020) · Cochrane
no estimate extractedNRNo studies
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
250 mg magnesium oxide supplement vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
250 mg magnesium oxide supplement vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
250 mg magnesium oxide supplement vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
250 mg magnesium oxide supplement vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
250 mg magnesium oxide supplement vs placebo
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Magnesium and vitamin E co‐supplementation vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Magnesium and vitamin E co‐supplementation vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Magnesium and vitamin E co‐supplementation vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Magnesium and vitamin E co‐supplementation vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Magnesium and vitamin E co‐supplementation vs placebo
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin D vs placebo
Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin D vs placebo
Quality of life · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin D vs placebo
Adverse events · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin D vs placebo
Development of any new foot ulcers · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin D vs placebo
Amputation rate · people with diabetes and foot ulcers
Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane
no estimate extractedNRNo studies