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What do systematic reviews say?

1,333 questions · 1,344 findings · 217 reviews · All outcomes

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No studies found 1,344 · 100%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Prophylactic aciclovir (oral or intravenous) vs placebo

Recurrence of lesions · Patients being treated for cancer (predominantly haematological malignancies)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer 2009 · Cochrane All outcomes
Recurrence of lesions was a planned secondary outcome; no included trial reported data for this outcome in the prophylactic aciclovir versus placebo comparison.
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Adverse events · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Chronic pain · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
After 3 weeks
Planned primary outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our…
0 studies
No studies found

Arthrocentesis and lavage vs Arthroscopy

Maximum bite force · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

The review found no eligible studies for this question.

1 finding from 1 review

Arthrocentesis and lavage for treating temporomandibular joint disorders 2009 · Cochrane All outcomes
To date, no randomised controlled trial in this area reported maximum bite force.
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Complete remission · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Status of occlusion (e.g. ANB, Angle's classification, Wits analysis) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
Up to 3 years postoperatively
Planned secondary outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our…
0 studies
No studies found

Any denture cleansing method (mechanical or chemical) vs Another method, sham/placebo, or no treatment

Outcome not reported · Wearers of removable partial dentures (RPD), over the age of 18

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
No included study assessed removable partial denture (RPD) wearers; all six included trials assessed complete denture wearers (Discussion; Implications for research: 'No included study assessed removable partial…
0 studies
No studies found

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects 2009 · Cochrane All outcomes
1 year (time-points 1, 5 and 10 years planned)
Radiographic bone level: no trial evaluated this.
0 studies
No studies found

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects 2009 · Cochrane All outcomes
1 year (time-points 1, 5 and 10 years planned)
SoF (Emdogain vs GTR): Aesthetics - See comment; 0 [0]; No studies reported this.
0 studies
No studies found

Aciclovir (oral or intravenous) for treatment vs placebo

Cost of oral care · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients / immunocompromised)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer 2009 · Cochrane All outcomes
For the treatment comparison (aciclovir versus placebo), no data were available for recurrence of lesions, amount of analgesia, days of stay in hospital, cost of oral care or patient quality of life.
0 studies
No studies found

Dental fillings (restorations) vs No treatment

Outcome not reported · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

The review found no eligible studies for this question.

1 finding from 1 review

Dental fillings for the treatment of caries in the primary dentition 2009 · Cochrane All outcomes
Minimum 6 months follow-up
"No studies were found that compared restorations versus extractions or no treatment as an intervention in children with caries in the primary dentition."
Studies not reported
No studies found

Ultrasonic treatment or microwave disinfection device vs Another method, sham/placebo, or no treatment

Outcome not reported · Adults (over 18) wearing complete dentures (CD) or removable partial dentures (RPD)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
The effectiveness of ultrasonic or microwave devices as an intervention for routine use was not studied according to a randomised controlled trial design (Implications for research).
0 studies
No studies found

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Healing and union of fracture (versus mal-union and non-union) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
Up to 3 years postoperatively
Planned primary outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our…
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Partial reduction · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Recurrence · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Patient acceptability of treatment and its side effects · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Quality of life (validated questionnaire) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
No data were available for this patient-reported outcome in the single included trial.
0 studies
No studies found

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth 2008 · Cochrane All outcomes
No eligible randomised controlled trials were identified.
Studies not reported
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Instrumental assessment: nasalance score (nasometry and pressure-flow measure) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
Nasalance score by nasometry and pressure-flow measure: the single included trial (Ysunza 2001) provided no data for this outcome.
0 studies
No studies found