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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Nanofiltered C1 esterase inhibitor vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Nanofiltered C1 esterase inhibitor vs placebo or active control
Serious adverse events (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Nanofiltered C1 esterase inhibitor vs placebo or active control
Adverse events (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Recombinant human C1 esterase inhibitor vs placebo or active control
Risk of HAE attacks (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Recombinant human C1 esterase inhibitor vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Recombinant human C1 esterase inhibitor vs placebo or active control
Quality of lifestandardised mean difference(during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Recombinant human C1 esterase inhibitor vs placebo or active control
Disability(any validated scale)(during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Lanadelumab vs placebo or active control
Risk of HAE attacks (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Lanadelumab vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Avoralstat vs placebo
Disability (any validated scale) (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cemented modern unipolar hemiarthroplasty · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cemented modern unipolar hemiarthroplasty · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cemented modern unipolar hemiarthroplasty · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Dynamic fixed angle plate · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Dynamic fixed angle plate · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Functional status, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Mobility, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Activities of daily living, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Number of cannulation attempts · adults undergoing peripheral venous cannulation classed as moderately difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Patient satisfaction NRS from 0 to 10 or 4‐step Likert scaleThe higher the score the higher the level of satisfaction · adults undergoing peripheral venous cannulation classed as moderately difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Overall success of cannulation · adults undergoing peripheral venous cannulation classed as easya
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Number of cannulation attempts · adults undergoing peripheral venous cannulation classed as easya
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Patient satisfaction NRS from 0 to 10 or 4‐step Likert scale The higher the score, the higher the level of satisfaction · adults undergoing peripheral venous cannulation classed as easya
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Overall success of cannulation · adults undergoing peripheral venous cannulation classed as moderately difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Zinc oxide mesh vs placebo mesh
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Zinc oxide mesh vs placebo mesh
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Zinc oxide mesh vs placebo mesh
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Zinc oxide mesh vs placebo mesh
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies