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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
601 questions in 75 reviews · Schizophrenia
current versionsNo studies 601 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
HALOPERIDOL vs BENZODIAZEPINE: a. FLUNITRAZEPAM Tranquillisation or asleep ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: a. FLUNITRAZEPAM Repeated need for tranquillisation within 24 hours ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: a. FLUNITRAZEPAM Economic outcome ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: b. LORAZEPAM Specific behaviour ‐ threat or injury to self or others within 24 hours ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: b. LORAZEPAM Economic outcome ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: c. MIDAZOLAM Tranquillisation or asleep ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: c. MIDAZOLAM Repeated need for rapid tranquillisation ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: c. MIDAZOLAM Specific behaviour ‐ threat or injury to self or others ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs BENZODIAZEPINE: c. MIDAZOLAM Economic outcome ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs COMBINATIONS: a. HALOPERIDOL + LEVOMEPROMAZINE Tranquillisation or asleep ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
HALOPERIDOL vs COMBINATIONS: a. HALOPERIDOL + LEVOMEPROMAZINE Repeated need for tranquillisation ‐ not reported · patients with psychosis‐induced aggression or agitation Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Clinically important changes in global state · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Aggression ‐ Improved to an important extent · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Aggression ‐ deterioration: incidence of violence to self or others · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Aggression ‐ changes in aggression as recorded by any other outcomes · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Adverse effects ‐ physical adverse effects · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Adverse effects ‐ death, suicide or natural causes · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
De‐escalation for aggression thought to be due to psychosis vs standard care Adverse effects ‐ psychological adverse effects · people who are aggressive secondary to serious mental illness De‐escalation techniques for psychosis‐induced aggression or agitation (2017) · Cochrane | no estimate extracted | NR | No studies |
Communication skills training vs no specific training Adherence to Adherence to treatment: taking of medication, attending appointments · psychiatrists and people with schizoaffective disorder or schizophrenia Communication skills training for mental health professionals working with people with severe mental illness (2017) · Cochrane | no estimate extracted | NR | No studies |
Communication skills training vs no specific training Global State: clinically important improvement · psychiatrists and people with schizoaffective disorder or schizophrenia Communication skills training for mental health professionals working with people with severe mental illness (2017) · Cochrane | no estimate extracted | NR | No studies |
Communication skills training vs no specific training Service Use: hospital admission, days in hospital · psychiatrists and people with schizoaffective disorder or schizophrenia Communication skills training for mental health professionals working with people with severe mental illness (2017) · Cochrane | no estimate extracted | NR | No studies |
Communication skills training vs no specific training Quality of Life: clinically important improvement · psychiatrists and people with schizoaffective disorder or schizophrenia Communication skills training for mental health professionals working with people with severe mental illness (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage Adverse events · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage Leaving the study early · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage Economic costs · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture (b) Change in the frequency of defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture (c) Change in straining at defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture (d) Change in the frequency of lumpy or hard stools · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture (e) Change in the frequency of manual manoeuvres to facilitate defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Need for rescue medication · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Presence of antipsychotic‐related constipation complications such as bowel obstruction · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Quality of life (changed to any extent) · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Adverse events · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Leaving the study early · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs acupuncture Economic costs · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda (b) Change in the frequency of defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda (c) Change in straining at defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda (d) Change in the frequency of lumpy or hard stools · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda (e) Change in the frequency of manual manoeuvres to facilitate defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage (b) Change in the frequency of defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda Need for rescue medication · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda Presence of antipsychotic‐related constipation complications such as bowel obstruction · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda Quality of life (changed to any extent) · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda Leaving the study early · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Mannitol vs phenolphthalein or rhubarb soda Economic costs · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage (c) Change in straining at defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage (d) Change in the frequency of lumpy or hard stools · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage (e) Change in the frequency of manual manoeuvres to facilitate defecation · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage Need for rescue medication · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |
Glycerol laxative vs tuina massage Presence of antipsychotic‐related constipation complications such as bowel obstruction · antipsychotic‐related constipation Pharmacological treatment for antipsychotic‐related constipation (2017) · Cochrane | no estimate extracted | NR | No studies |