Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

555 questions in 79 reviews · Musculoskeletal

current versions
No studies 555 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Relaxation vs usual care
Adverse events post‐intervention ‐ not reported · patients with fibromyalgia
Mind and body therapy for fibromyalgia (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs no brace
Treatment failure · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs no brace
Serious adverse events · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Lateral wedge insole vs neutral insole
Treatment failure · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Lateral wedge insole vs neutral insole
Serious adverse events · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Lateral wedge insole vs neutral insole
Total number of adverse events · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs lateral wedge insole
Stiffness · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs lateral wedge insole
Health‐related quality of life · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs lateral wedge insole
Treatment failure · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs lateral wedge insole
Serious adverse events · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs lateral wedge insole
Total number of adverse events · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Valgus knee brace vs no brace
Stiffness · patients with varus medial osteoarthritis of the knee
Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR)
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR)
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR)
Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Pain ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Physical function ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)
Trapeziometacarpal joint imaging ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing
Physical function ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing
Trapeziometacarpal joint imaging ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T)
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)
Physical function ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)
Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)
Trapeziometacarpal joint imaging ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Pain ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Physical function ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T)
Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)
Trapeziometacarpal joint imaging ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T)
Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR)
Pain ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis
Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
ASAS partial remission
TNF‐alpha inhibitors for ankylosing spondylitis (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Radiographic progression
TNF‐alpha inhibitors for ankylosing spondylitis (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Withdrawals due to adverse events
TNF‐alpha inhibitors for ankylosing spondylitis (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Serious adverse events
TNF‐alpha inhibitors for ankylosing spondylitis (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy
Outcomesa · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 2: comparison of operation types: late results of needle fasciotomy vs limited fasciectomy
Major outcome group 5 (adverse effects)d · 93 participants (van Rijssen 2012a)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 3: comparison of operation types: firebreak skin grafting vs z‐plasty closure of fasciectomy
Major outcome group 2 (patient satisfaction and other PROM) · 79 participants (Ullah 2009)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 4: refining rehabilitation: three months of postoperative night splinting with hand therapy vs hand therapy alone
Major outcome group 2 (patient satisfaction) · 210 participants with Dupuytren's disease of the fingers in 2 studies (225 digits reported across all studies) (Collis…
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 4: refining rehabilitation: three months of postoperative night splinting with hand therapy vs hand therapy alone
Major outcome group 4 (recurrence) · 210 participants with Dupuytren's disease of the fingers in 2 studies (225 digits reported across all studies) (Collis…
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy
Major outcome group 4 (recurrence) · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies