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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

432 questions in 71 reviews · Neonatal

current versions
No studies 432 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Mask vs prongs
Neurodevelopmental impairment · preterm infants receiving nasal CPAP
Masks versus prongs as interfaces for nasal continuous positive airway pressure in preterm infants (2022) · Cochrane
no estimate extractedNRNo studies
Prophylactic CPAP vs very early CPAP
Failed treatment · preterm infants
Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane
no estimate extractedNRNo studies
Prophylactic CPAP vs very early CPAP
Combined outcome of death and bronchopulmonary dysplasia · preterm infants
Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane
no estimate extractedNRNo studies
Prophylactic CPAP vs very early CPAP
Intraventricular haemorrhage grade 3 or 4 · preterm infants
Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane
no estimate extractedNRNo studies
Prophylactic CPAP vs very early CPAP
Neurodevelopmental impairment · preterm infants
Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane
no estimate extractedNRNo studies
Prophylactic or very early CPAP vs supportive care
Neurodevelopmental impairment · preterm infants
Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs diazepam
Neonatal and infant mortality · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs diazepam
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs diazepam
Adverse events To discharge · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs chlorpromazine
Neonatal and infant mortality · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs chlorpromazine
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs chlorpromazine
Days' pharmacological treatment · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital and opioid vs opioid alone
Neonatal and infant mortality · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital and opioid vs opioid alone
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital and opioid vs opioid alone
Days' pharmacological treatment · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital and opioid vs opioid alone
Adverse events To discharge · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs supportive care
Neonatal and infant mortality · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Clonidine and opioid vs opioid alone
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Clonidine and opioid vs opioid alone
Days' hospitalisation · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Clonidine and opioid vs phenobarbital and opioid
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs supportive care
Neurodevelopmental disability · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs supportive care
Adverse events To discharge · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Phenobarbital vs diazepam
Seizures To discharge · newborn infants with opioid withdrawal
Sedatives for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs methadone
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs methadone
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs buprenorphine
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs buprenorphine
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs dilute tincture of opium
Treatment failure · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs dilute tincture of opium
Seizures · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs dilute tincture of opium
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs dilute tincture of opium
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs dilute tincture of opium
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo or no treatment / usual care
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs clonidine
Seizures · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs clonidine
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs clonidine
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs clonidine
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs diazepam
Seizures To discharge · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs diazepam
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs diazepam
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo or no treatment / usual care
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs diazepam
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs phenobarbital
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs phenobarbital
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs chlorpromazine
Neonatal or infant mortality · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs chlorpromazine
Neurodevelopmental disability · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs chlorpromazine
Days hospitalisation · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo or no treatment / usual care
Adverse events (treatment‐related) To discharge · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
Morphine vs methadone
Seizures · newborn infants with opioid withdrawal
Opioid treatment for opioid withdrawal in newborn infants (2021) · Cochrane
no estimate extractedNRNo studies
High MCT formula vs low MCT formula
Neurodevelopmental outcomes · promoting short‐term growth of preterm infants
High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm… (2021) · Cochrane
no estimate extractedNRNo studies