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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

111 questions in 14 reviews · Endodontics and dental trauma

current versions
No studies 111 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Sodium hypochlorite 1% with chlorhexidine 2% final rinse vs Sodium hypochlorite 1% with normal saline final rinse
Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies
Sodium hypochlorite 5% vs Sodium hypochlorite 5% with proteolytic enzyme
Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies
Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel)
Change in periapical radiolucency (radiography or CBCT), up to 1 year after treatment · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies
Sodium hypochlorite 5% (also 2.5%) vs Sodium hypochlorite 1%
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies
Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse
Change in periapical radiolucency (radiography or CBCT), up to 1 year after treatment · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies
Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)
Outcome NR · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of…
Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth (2008) · Cochrane
No eligible randomised controlled trials were identified.NRNo studies
Hand instrumentation in conjunction with (as an adjunct to) an ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal vs Hand instrumentation used alone (files and reamers used manually)
Outcome NR · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of…
Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth (2008) · Cochrane
No eligible randomised controlled trials were identified.NRNo studies
Prefabricated metal post and core (Category II) vs Metal custom-cast post and core (Category I)
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial compared metal-cast posts with prefabricated metal posts (a planned primary comparison); no eligible study identified.0 studiesNo studies
Metal post of one alloy type vs Metal post of a different alloy type
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial evaluated alloy type in metal posts (a planned secondary comparison); no eligible study identified.0 studiesNo studies
Cast post and core with a diaphragm vs Cast post and core without a diaphragm
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial evaluated the presence of a diaphragm in cast posts (a planned secondary comparison); no eligible study identified.0 studiesNo studies
Post and core restoration with a ferrule vs Post and core restoration without a ferrule
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial evaluated the presence of a ferrule (a planned secondary comparison); no eligible study identified.0 studiesNo studies