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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
15,213 questions in 2,394 reviews
current versionsNo studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
One-to-one dietary intervention aimed at preventing tooth erosion (e.g., reducing consumption of acidic/carbonated drinks) vs No dietary advice, or different dietary advice Dental erosion / tooth wear (tooth wear indices) · Participants of any age receiving one-to-one dietary advice in a dental setting One‐to‐one dietary interventions undertaken in a dental setting to change dietary behaviour (2012) · Cochrane | There were no studies concerned with dietary change aimed at preventing tooth erosion. | 0 studies | No studies |
Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline Proportion of participants with moderate to severe pain up to 6 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs No intervention or another treatment technique Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome) · Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with… Treatments for adults with prominent lower front teeth (2012) · Cochrane | No included study measured the planned primary outcome. Discussion: 'The primary outcome proposed for this review was to evaluate the effectiveness of treatments for prognathism, but none of the studies conclusively… | NR | No studies |
HAART regimen + topical treatment vs HAART regimen alone Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers Topical treatments for HIV‐related oral ulcers (2012) · Cochrane | No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6… | 0 studies | No studies |
Sodium hypochlorite 1% with chlorhexidine 2% final rinse vs Sodium hypochlorite 1% with normal saline final rinse Adverse effects · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel) Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Antipyretic drugs vs no antipyretic drug or placebo Adverse Events · patients with fever in malaria Antipyretic measures for treating fever in malaria (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ NON‐SPECIFIC: SELEGILINE vs PLACEBO Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ NON‐SPECIFIC: SELEGILINE vs PLACEBO Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE Adverse effects: Extrapyramidal symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO Quality of life Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO Adverse effects: Death Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO Adverse effects: Psychotic symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL vs PLACEBO Adverse effects: Extrapyramidal symptoms Not reported · patients with sexual dysfunction due to antipsychotic drug therapy Management of sexual dysfunction due to antipsychotic drug therapy (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Function · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Tenderness · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Global Perceived Effect · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Satisfaction · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Overall well‐being · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse effects · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Function · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Tenderness · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Function · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Global Perceived Effect · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Satisfaction · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Overall well‐being · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse effects · Patients with unknown duration of mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Tenderness · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Global Perceived Effect · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Satisfaction · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Overall well‐being · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse effects · Patients with subacute/chronic mechanical neck pain Massage for mechanical neck disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Morbidity · Patients with type 2 diabetes mellitus Self‐monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · patients with type 2 diabetes mellitus Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse effects · patients with type 2 diabetes mellitus Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Costs · patients with type 2 diabetes mellitus Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Neurological sequelae at day 28 · Adults with severe malaria Artesunate versus quinine for treating severe malaria (2012) · Cochrane | no estimate extracted | NR | No studies |
CBT vs no treatment Outcomes3 · patients with adjustment disorders Interventions to facilitate return to work in adults with adjustment disorders (2012) · Cochrane | no estimate extracted | NR | No studies |
BENZODIAZEPINES AS SOLE TREATMENT vs PLACEBO Number of participants tranquillised at endpoint of the study (Desired sedation/tranquillisation) · people with schizophrenia Benzodiazepines for schizophrenia (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR SAEs ‐ formoterol versus salbutamol · patients with chronic asthma (children) Regular treatment with formoterol for chronic asthma: serious adverse events (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Death from any cause ( · patients with diabetes mellitus Cinnamon for diabetes mellitus (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Morbidity ( · patients with diabetes mellitus Cinnamon for diabetes mellitus (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life ( · patients with diabetes mellitus Cinnamon for diabetes mellitus (2012) · Cochrane | no estimate extracted | NR | No studies |