Findings

What do systematic reviews say?

1,333 questions · 1,344 findings · 217 reviews · All outcomes

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No studies found 1,344 · 100%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Laser enamel preparation vs Enameloplasty

Any planned outcome (sealant retention, caries, etc.) · Patients with premolars/molars requiring pit-and-fissure sealants

No eligible studies compared laser preparation with enameloplasty for fissure sealant placement (evidence gap).

1 finding from 1 review

The clinical effects of laser preparation of tooth surfaces for fissure sealants placement: a systematic review and… 2019 All outcomes
Clinical (in vivo pit-and-fissure sealant placement)
no estimate extracted
0 studies
No studies found

1000 mg champignon extract vs placebo

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
mean 2 weeks
Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
0 studies
No studies found

Slow-release fluoride device (fluoride glass beads) vs Fluoride mouthrinse

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes
At debond (end of orthodontic treatment)
Additional SoF Table 3. Number of participants with more severe DLs: none of the trials reported this outcome.
0 studies
No studies found

1450 ppm F toothpaste vs 250 ppm F toothpaste

Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Adverse effects of toothpaste: no studies reported this outcome.
0 studies
No studies found

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

Quality of life · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
Quality of life was a prespecified secondary outcome. None of the 44 included studies in the review (across all comparisons) reported quality-of-life data (review-wide evidence gap).
0 studies
No studies found

Treatment with antibiotics vs No antibiotics, placebo, or different types of antibiotics

Outcome not reported · People with avulsed and replanted permanent (front) teeth

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing

Interproximal caries · Adults, 16 years and older (dentate)

The review found no eligible studies for this question.

1 finding from 1 review

Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
No included study assessed caries as an outcome.
0 studies
No studies found

Interdental brushing plus toothbrushing vs Toothbrushing alone

Interproximal caries · Adults, 16 years and older (dentate)

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
No included study assessed caries as an outcome.
0 studies
No studies found
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults 2013 · Cochrane All outcomes
Not estimable. No included study assessed caries as an outcome. (See comment)
0 studies
No studies found

Laser (low-level laser) at P6 point vs sham control

Completion of dental treatment · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled children

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
Completion of dental treatment: none of the trials reported this outcome.
0 studies
No studies found

Hinokitiol gel vs Placebo gel

Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
mean 4 weeks
Patient-reported OLT score: listed in the Summary of findings table but no data reported. No data were reported for patient-reported OLT score.
0 studies
No studies found

Systemic antibiotic (oral penicillin 500 mg) plus analgesic vs Placebo plus analgesic

Number of adverse events · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic use for irreversible pulpitis 2019 · Cochrane All outcomes
Number of adverse events: Outcome not reported.
Studies not reported
No studies found

Patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily vs 0 ppm F placebo mouthrinse, daily

Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes
At debond (end of orthodontic treatment)
SoF 4. Adverse effects: none of the trials reported this outcome.
0 studies
No studies found

Acupressure at P6 point with sea band plus sedation vs Sham (dummy) acupressure with sedation

Presence or absence of gagging · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
0 studies
No studies found

Chlorhexidine + zinc acetate mouthwash vs Placebo mouthwash

Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
mean 3 months
Patient-reported OLT score: listed in the Summary of findings table but no data reported. No data were reported for patient-reported OLT score.
0 studies
No studies found

1000 or 1100 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste

Proportion developing new caries · Adults with mature permanent dentition (aged 18 to 93 years at study start)

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Proportion of adults developing new caries: no studies reported this outcome.
0 studies
No studies found

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)

Bleeding duration · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… 2019 · Cochrane All outcomes
This outcome was not reported in either of the trials.
0 studies
No studies found

Acupressure at P6 point with device vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported adverse effects.
0 studies
No studies found

Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported adverse effects.
0 studies
No studies found

Acupressure at P6 point with thumb plus sedation vs Sham (dummy) acupressure with sedation

Presence or absence of gagging · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
0 studies
No studies found

Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation

Presence or absence of gagging · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
0 studies
No studies found