Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

856 questions in 87 reviews · Cystic Fibrosis and Genetic Disorders

current versions
No studies 856 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Tinzaparin vs placebo
Number of serious complications of SCD ‐ not measured · people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Tinzaparin vs placebo
Number of other sickle‐related events ‐ not measured · people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Tinzaparin vs placebo
Quality of life (e.g. absence from school, lost time at work, mobility) as assessed by any validated questionnaire either generic or SCD specific) ‐ not measured · people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Tinzaparin vs placebo
Participant satisfaction with the medication assessed by any appropriate and validated questionnaire (either generic or SCD specific) ‐ not measured · people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe allergic reaction · persons with severe haemophilia A and factor inhibitory antibodies
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Nephrotic symdrome · persons with severe haemophilia A and factor inhibitory antibodies
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B (2014) · Cochrane
no estimate extractedNRNo studies