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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
856 questions in 87 reviews · Cystic Fibrosis and Genetic Disorders
current versionsNo studies 856 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings: nitric oxide vs placebo Inflammatory markers · children (12 or over) and young adults with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Zinc supplementation vs placebo QoL · children with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Zinc supplementation vs placebo Sputum microbiology · children with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: Zinc supplementation vs placebo Inflammatory markers · children with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: β‐carotene vs placebo Need for antibiotics see pulmonary exacerbations · children and adults with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: β‐carotene vs placebo QoL · children and adults with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: β‐carotene vs placebo Sputum microbiology · children and adults with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: β‐carotene vs placebo Inflammatory markers · children and adults with cystic fibrosis Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: garlic supplementation vs placebo Pulmonary exacerbations · children aged over eight and adults with cystic fibrosis and chronic pulmonary infection with P aeruginosa Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECT Change in BMI · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECT Adverse events · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECT Pulmonary exacerbations · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECMM Change in weight · children with cystic fibrosis and proven pancreatic insufficiency Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECMM Change in height · children with cystic fibrosis and proven pancreatic insufficiency Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECMM Change in BMI · children with cystic fibrosis and proven pancreatic insufficiency Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs NECT plus cimetidine Change in height · adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECMM Adverse events · children with cystic fibrosis and proven pancreatic insufficiency Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECMM Pulmonary exacerbations · children with cystic fibrosis and proven pancreatic insufficiency Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM (Creon®) vs a different ECM Change in height · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM (Creon®) vs a different ECM Change in BMI · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM (Creon®) vs a different ECM Pulmonary exacerbations · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs NECT plus cimetidine Change in BMI · adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs TPE Change in height · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs TPE Change in BMI · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs TPE Frequency of bowel symptoms · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs TPE Adverse events · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs TPE Pulmonary exacerbations · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs other enteric‐coated preparations Change in BMI · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs other enteric‐coated preparations Adverse events · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs other enteric‐coated preparations Pulmonary exacerbations · children with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: low‐dose vs high‐dose PERT Change in height · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: low‐dose vs high‐dose PERT Change in BMI · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: low‐dose vs high‐dose PERT Pulmonary exacerbations · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: liprotamase vs porcine PERT Change in height · children aged 7 years or over and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: liprotamase vs porcine PERT Change in BMI · children aged 7 years or over and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs NECT plus cimetidine Adverse events · adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs NECT plus cimetidine Pulmonary exacerbations · adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: ECM vs ECT Change in height · children and adults with cystic fibrosis Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Participant‐reported · children and adults with asthma diagnosed by American Thoracic Society criteria Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Investigator‐reported · children with ADHD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo All‐cause mortality · children with ADHD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Serious adverse events · children with ADHD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Participant‐reported · adults with CVD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Investigator‐reported · adults with CVD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo All‐cause mortality · adults with CVD Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Participant‐reported · adults with CVI Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Investigator‐reported · adults with CVI Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo All‐cause mortality · adults with CVI Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs placebo Serious adverse events · adults with CVI Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |
Pine bark extract vs control Participant‐reported · adults with diabetes mellitus type I Pine bark (Pinus spp.) extract for treating chronic disorders (2020) · Cochrane | no estimate extracted | NR | No studies |