What do systematic reviews say?

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with clinically diagnosed seizures

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with EEG‐confirmed seizures

Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with clinically diagnosed seizures

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with clinically diagnosed seizures

Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with EEG‐confirmed seizures

Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with EEG‐confirmed seizures

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates with clinically diagnosed seizures

Mortality or neurodevelopmental disability at 18 to 24 months' corrected age ‐ not reported · neonates

Major neurodevelopmental disability in children aged 18 to 24 months or three to five years old ‐ not reported · postoperative pain in neonates

Cognitive and educational outcomes in children more than five years old ‐ not reported · postoperative pain in neonates

Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in neonates

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in neonates

All‐cause mortality during initial hospitalization ‐ not reported · postoperative pain in neonates

Major neurodevelopmental disability in children aged 18 to 24 months or three to five years old ‐ not reported · postoperative pain in neonates

Cognitive and educational outcomes in children more than five years old ‐ not reported · postoperative pain in neonates

Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in neonates

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in neonates

Pain · postoperative pain in neonates

All‐cause mortality during initial hospitalization ‐ not reported · postoperative pain in neonates