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What do systematic reviews say?

108 questions · 110 findings · 36 reviews · Oral Health

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No studies found 110 · 100%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Thermoelastic copper NiTi (CuNiTi) arch wire vs Conventional (stabilised) NiTi arch wire

Pain · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

The review found no eligible studies for this question.

1 finding from 1 review

Initial arch wires used in orthodontic treatment with fixed appliances 2024 · Cochrane All outcomes
Pain: not reported
0 studies
No studies found

Single-strand superelastic NiTi arch wire vs Coaxial superelastic NiTi arch wire

Pain · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

The review found no eligible studies for this question.

1 finding from 1 review

Initial arch wires used in orthodontic treatment with fixed appliances 2024 · Cochrane All outcomes
Pain: not reported
0 studies
No studies found

ART using composite resin vs Conventional treatment using composite resin

Pain · Children with carious primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries 2017 · Cochrane All outcomes
Pain: Not measured.
0 studies
No studies found

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Pain · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

The review found no eligible studies for this question.

1 finding from 1 review

Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries 2017 · Cochrane All outcomes
Pain: Not measured.
0 studies
No studies found

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Hall technique vs Non-restorative caries treatment

Pain · Children with decayed primary molar teeth

The review found no eligible studies for this question.

1 finding from 1 review

Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
Pain: No evidence available (Summary of findings 2).
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Pain · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Pain': This outcome was not reported in the included studies.
0 studies
No studies found

Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical thalidomide vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

HAART regimen + topical treatment vs HAART alone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Relief of pain · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Relief of pain · Patients with cancer receiving chemotherapy and/or radiotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
No trial reported this planned secondary outcome for any comparison in this review
Studies not reported
No studies found

Topical triamcinolone acetonide vs Topical tacrolimus

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-8 weeks
Summary of findings 2: 'No data for this outcome' (triamcinolone vs tacrolimus, pain resolution)
0 studies
No studies found

Coronectomy vs Complete extraction (odontectomy)

Postoperative pain · Adults with mandibular third molars requiring removal

The review found no eligible studies for this question.

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
24 hours
no estimate extracted
Studies not reported
No studies found

Horizontal mattress / fibrin sealant suturing vs Conventional (simple interrupted) suturing

Postoperative pain · Adults with mandibular third molars requiring removal

The review found no eligible studies for this question.

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
24 hours
no estimate extracted
Studies not reported
No studies found

Lingual nerve retractor (subperiosteal or Free's) vs No retractor

Postoperative pain · Adults with mandibular third molars requiring removal

The review found no eligible studies for this question.

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
24 hours
no estimate extracted
Studies not reported
No studies found

Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)

Muscle pain at rest · People with temporomandibular disorders (TMD)

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
Listed in Summary of findings 4 as 'Not reported'; this outcome was not reported by any included study for this comparison.
0 studies
No studies found

Occlusal splint vs Pharmacological therapy

Muscle pain at rest · People with temporomandibular disorders (TMD)

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
Listed in Summary of findings 6 as 'Not reported'; this outcome was not reported by any included study for this comparison.
0 studies
No studies found

Occlusal splint vs acupuncture

Muscle pain at rest · People with temporomandibular disorders (TMD)

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for managing temporomandibular disorders 2024 · Cochrane All outcomes
Listed in Summary of findings 5 as 'Not reported'; this outcome was not reported by any included study for this comparison.
0 studies
No studies found