Gap finder
Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
191 questions in 40 reviews · cluster CL0369
current versionsNo studies 1 · 0.5%Ungraded 190 · 99.5%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Composite: Preference for replacement over repair - Scenario 5: open margin · Coverage: Covering cost of minimally invasive treatment Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 3.09 [1.65, 5.79] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · HDI: Low Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 25.94 [1.88, 358.26] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · HDI: Very high Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.87 [1.32, 2.64] | 10 studies | Ungraded |
Intervention NR Postmenopausal osteoporosis with pathological fracture · DMFS, bias-corrected (MR-RAPS/Debiased IVW) From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. (2025) | OR 1.401 [1.040, 1.887] | NR | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Continent: Europe Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.32 [0.27, 0.37] | 6 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · HDI: Very high Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 19.06 [7.76, 46.80] | 10 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · HDI: High Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.85 [1.43, 2.39] | 7 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Coverage: Not covering Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 10.96 [6.53, 18.39] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Coverage: Covering cost of minimally invasive treatment Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.76 [1.38, 2.24] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Coverage: Not covering Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 18.78 [8.63, 40.89] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Coverage: Covering cost of minimally invasive treatment Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 34.41 [16.26, 72.86] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Continent: Africa Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.57 [1.31, 1.87] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 5: open margin · Continent: Africa Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 7.59 [3.13, 18.38] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · HDI: Low Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.47 [0.87, 2.48] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Continent: South America Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 8.17 [2.20, 30.35] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Continent: Asia Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.38 [0.26, 0.56] | 11 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · HDI: Low Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 8.50 [6.23, 11.61] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Continent: Africa Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 14.98 [4.84, 46.32] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · HDI: High Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.79 [0.70, 0.88] | 7 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 5: open margin · Continent: South America Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 5.15 [3.98, 6.66] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Coverage: Covering cost of minimally invasive treatment Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 4.09 [2.77, 6.04] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 6: corrosion · Coverage: Not covering Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.54 [1.12, 2.12] | NR | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · HDI: High Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.85 [0.72, 1.00] | 7 studies | Ungraded |
Intervention NR Clinical and radiographic success rate · Full meta-regression: follow-up duration Partial pulpotomy for carious pulp exposure in adult mature permanent teeth: a systematic review and… (2025) | Meta-regression No significant association | NR | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · Coverage: Not covering Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.66 [0.49, 0.90] | NR | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Continent: South America Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.70 [0.60, 0.81] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Coverage: Not covering Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 3.85 [2.51, 5.93] | NR | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Continent: Africa Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.86 [0.74, 1.00] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 5: open margin · Continent: Asia Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 3.71 [2.01, 6.82] | 11 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · HDI: Low Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.75 [0.64, 0.87] | 2 studies | Ungraded |
Intervention NR Tooth loss and dental symptoms (cracked teeth, toothache) associated with e-cigarette use · Yang et al. [31] An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025) | Qualitative (narrative synthesis) Increased tooth loss and dental symptoms with daily e-cigarette use | 1 study | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 6: corrosion · Continent: Asia Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.69 [1.12, 2.55] | 11 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · HDI: Low Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.12 [0.68, 1.86] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 6: corrosion · Continent: Europe Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.28 [0.91, 1.81] | 6 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Continent: Asia Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 8.67 [5.32, 14.13] | 11 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 5: open margin · HDI: High Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 6.16 [5.32, 7.14] | 7 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Continent: South America Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 2.12 [0.66, 6.82] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · HDI: High Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.39 [0.26, 0.58] | 7 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · HDI: Medium Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.29 [0.07, 1.21] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · HDI: Medium Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 0.88 [0.14, 5.56] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · HDI: Medium Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 12.93 [8.77, 19.05] | 2 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 5: open margin · Continent: Europe Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 4.04 [2.03, 8.06] | 6 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Continent: Asia Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 18.59 [7.66, 45.10] | 11 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 6: corrosion · HDI: Very high Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.54 [1.03, 2.32] | 10 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Continent: Europe Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 2.03 [1.35, 3.04] | 6 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · Continent: South America Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 7.54 [3.41, 16.67] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 6: corrosion · Coverage: Covering cost of minimally invasive treatment Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 1.66 [1.11, 2.49] | NR | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 5: open margin · Continent: Africa Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 6.44 [4.85, 8.56] | 2 studies | Ungraded |
Intervention NR Amalgam: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · Continent: Europe Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 3.53 [2.36, 5.30] | 6 studies | Ungraded |
Intervention NR Composite: Preference for replacement over repair - Scenario 5: open margin · HDI: Very high Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… (2025) | RR 4.75 [2.78, 8.11] | 10 studies | Ungraded |