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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
108 questions in 53 reviews · cluster CL0291
current versionsNo studies 59 · 54.6%Ungraded 36 · 33.3%Very low 7 · 6.5%Low 1 · 0.9%Moderate 0 · 0%High 5 · 4.6%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Arthrocentesis and lavage vs Arthroscopy Quality of life · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without… Arthrocentesis and lavage for treating temporomandibular joint disorders (2009) · Cochrane | No data about quality of life were reported by the included trials. | 0 studies | No studies |
Aciclovir (oral or intravenous) for treatment vs Placebo Patient quality of life · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients /… Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer (2009) · Cochrane | For the treatment comparison (aciclovir versus placebo), no data were available for recurrence of lesions, amount of analgesia, days of stay in hospital, cost of oral care or patient quality of life. | 0 studies | No studies |
Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty) Quality of life (self or carer evaluated, validated questionnaires) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic… Interventions for the management of submucous cleft palate (2008) · Cochrane | No data were available for this patient-reported outcome in the single included trial. | 0 studies | No studies |
Systemic oral acyclovir vs Placebo or no treatment Quality of life (assessed by a validated questionnaire) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis) Acyclovir for treating primary herpetic gingivostomatitis (2008) · Cochrane | No data were available in either included study (Amir 1997b; Ducoulombier 1988). | NR | No studies |
Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Placebo or no treatment Patient quality of life · Patients with cancer receiving chemotherapy or radiotherapy or both Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane | No trial reported this planned secondary outcome for any comparison in this review | NR | No studies |
Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery) Patient well-being / quality of life · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved… Guided tissue regeneration for periodontal infra-bony defects (2006) · Cochrane | Cortellini 2001: 36% of GTR patients reported the procedure interfered with daily activity for an average of 2.7 days versus 32% of controls for an average of 2.4 days; no significant difference for postoperative pain… | 1 study | Ungraded |
Stabilisation splint (SS) vs Non-occluding splint Quality of life · Patients with pain dysfunction syndrome (PDS) of all degrees of severity · 3 months or less Stabilisation splint therapy for temporomandibular pain dysfunction syndrome (2004) · Cochrane | RR 0.12 [0.02, 0.90] | 1 study | Ungraded |
Occlusal adjustment (OA) vs Placebo Quality of life · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD) Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane | There were no data on psychosocial outcomes, costs or quality of life in any of the trials. | 0 studies | No studies |