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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Implant failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in implant failure compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Branemark Mark II turned titanium screws vs ITI TPS hollow titanium screws

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Branemark Mark II turned titanium screws showed no clear difference in implant failure compared with ITI TPS hollow titanium screws; GRADE not reported.

1 finding from 1 review

Topical interventions (sucralfate, interferon-alpha, cyclosporin A) vs placebo

Episode duration associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • SoF (topical interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim): "5 placebo-controlled trials evaluated topical interventions (sucralfate suspension (2 trials), interferon-alpha (2…
    Studies not reported
    GRADE not reported

Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation

Prosthesis failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus

Maxillary sinus lift (augmentation) with long implants showed no clear difference in prosthesis failure compared with short implants (5 to 8.5 mm) without sinus augmentation (moderate certainty).

1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP

Partial graft loss · Patients with insufficient bone below the maxillary sinus requiring dental implants

Bone graft with platelet-rich plasma (PRP) showed no clear difference in partial graft loss compared with bone graft without PRP; GRADE not reported.

1 finding from 1 review

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Patient perceived satisfaction (denture preference) · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Self etching primer (one-step etchant-and-primer technique) vs Conventional etchants (two-step etch and prime method using 37% phosphoric acid)

Damage to the teeth (e.g. tooth decay) · Children and adults with fixed orthodontic brackets bonded to incisors, canines and premolars

The review found no eligible studies for this question.

1 finding from 1 review

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) vs paracetamol

Participant‐reported pain relief of 50% or greater · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher proportion of patients with >50% maximum pain relief (TOTPAR) over 6… compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).

1 finding from 1 review

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Pulp exposure during caries removal · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Partial caries removal (single stage; residual dentinal caries… probably leads to lower pulp exposure during caries removal compared with complete caries removal (moderate certainty).

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Treatment time · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Patient discomfort · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoral distalising appliance vs Another (different) intraoral distalising appliance

Number of visits to complete treatment · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

The review found no eligible studies for this question.

1 finding from 1 review

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Restoration failure · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

It is very uncertain whether partial caries removal (single stage; residual dentinal caries… changes failure of restorations compared with complete caries removal (very low certainty).

1 finding from 1 review

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Requirement for additional (surgical) interventions (plate removal within 90 days) · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach led to lower requirement for additional (surgical) interventions (plate removal… compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review