Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

NobelReplace Select Tapered implants vs NobelReplace implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelReplace Select Tapered implants showed no clear difference in implant failure compared with nobelReplace Groovy implants; GRADE not reported.

1 finding from 1 review

Autogenous bone graft (two-stage lateral sinus lift) vs Bone substitute (anorganic bovine bone / Bio-Oss)

Complications · Patients with an atrophic posterior maxilla requiring maxillary sinus augmentation

Autogenous bone graft (two-stage lateral sinus lift) showed no clear difference in complications compared with bone substitute (anorganic bovine bone / Bio-Oss); GRADE not reported.

1 finding from 1 review

Topical triamcinolone acetonide vs Phenytoin syrup mouthwash (30 mg in 5 mL)

Positive response (not defined) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Triamcinolone acetonide 0.1% ointment (topical) led to higher positive response (not defined) compared with phenytoin syrup mouthwash (30 mg in 5 mL); GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation

Patient preference · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Lip or cheek biting, numbness or allergy · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

ITI SLA standard (regular neck) implants vs ITI SLActive implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

ITI SLA standard (regular neck) implants showed no clear difference in implant failure compared with ITI SLActive implants; GRADE not reported.

1 finding from 1 review

Resorbable barrier (membrane) to seal the lateral window vs No membrane to seal the lateral window

Prosthesis failure · Patients undergoing lateral-window maxillary sinus lift

Resorbable barrier (membrane) to seal the lateral window showed no clear difference in prosthesis failure compared with no membrane to seal the lateral window; GRADE not reported.

1 finding from 1 review

Colchicine (systemic; 0.5 mg weight-adjusted daily) vs placebo

Total number of oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Colchicine (systemic; 0.5 mg weight-adjusted daily) showed no clear difference in total number of oral ulcers compared with placebo (moderate certainty).

1 finding from 1 review

Southern regular implants vs Southern wide implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Southern regular implants showed no clear difference in implant failure compared with southern wide implants; GRADE not reported.

1 finding from 1 review

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Bone gain · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in bone gain compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

4 findings from 1 review
Show 1 more finding

Turned (smoother) implant surfaces vs Roughened implant surfaces

Early implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Turned (smoother) implant surfaces showed no clear difference in early implant failure compared with roughened implant surfaces (low certainty).

1 finding from 1 review

Systemic interventions (aciclovir, thalidomide, corticosteroids, rebamipide, etanercept, colchicine, interferon-alpha) vs placebo

Pain associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • SoF 2 (systemic interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim; the review's wording "topical" is a typo for systemic): "8 placebo-controlled trials evaluated topical…
    Studies not reported
    GRADE not reported