Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) probably leads to lower clinical failure compared with calcium hydroxide (CH) (moderate certainty).

2 findings from 1 review

Composite (chemical or light cured) vs Resin-modified glass ionomer cement

Outcome not reported · Patients with fixed orthodontic appliances attached to their teeth

The review found no eligible studies for this question.

1 finding from 1 review
  • Adhesives for fixed orthodontic brackets 2018 · Cochrane All outcomes
    To end of appliance treatment
    No included studies involved a comparison with resin-modified glass ionomer cement (a planned adhesive group). The authors recommended future randomised controlled trials involving resin-modified light cured glass…
    0 studies
    No studies found

Autologous platelet concentrates (APC) + open flap debridement (OFD) + bone graft (BG) vs OFD + BG (open flap debridement + bone graft)

Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Calculus · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)

Routine scale and polish every 6 months leads to lower calculus compared with routine scale and polish every 12 months (high certainty).

1 finding from 1 review

Zinc oxide and eugenol (ZOE) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Zinc oxide and eugenol (ZOE) led to lower clinical failure compared with ZOE + calcium hydroxide + iodoform (unnamed product); GRADE not reported.

1 finding from 1 review

SPT performed by non-specialist clinicians (general dental practitioners under specialist prescription) vs SPT performed by specialists (specialist practice)

Tooth loss · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

The review found no eligible studies for this question.

1 finding from 1 review

Biodentine vs Propolis

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with propolis; GRADE not reported.

1 finding from 1 review

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Psychological status: social self-esteem (Culture-Free Self-Esteem Inventory subset); also general self-esteem and Social Avoidance and Distress Scale · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…
1 finding from 1 review

OrthoMTA vs RetroMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

OrthoMTA showed no clear difference in radiological failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

Alginate (two stage-two step final/wash impression) vs Silicone elastomer (two stage-two step)

Participant-reported quality of the denture (comfort, stability, chewing efficiency) · Completely edentulous people
1 finding from 1 review

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:80,000 epinephrine

Speed of onset of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:100,000 epinephrine changes speed of onset of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:80,000 epinephrine (very low certainty).

1 finding from 1 review

6% HP strip vs 10% HP thin-gel strip

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6% HP strip changes tooth whitening - assessed by the dentist compared with 10% HP thin-gel strip (very low certainty).

1 finding from 1 review

Harvold Activator vs Frankel function regulator

Occlusion (net change in overjet, short term) · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Harvold Activator led to lower overjet change compared with frankel function regulator; GRADE not reported.

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Prosthodontic maintenance: patrix replaced (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: patrix replaced (short term) compared with telescopic attachment system (very low certainty).

1 finding from 1 review

3% mepivacaine plain vs 2% lidocaine, 1:50,000 epinephrine

Speed of onset of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

3% mepivacaine plain showed no clear difference in speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:50,000 epinephrine (low certainty).

1 finding from 1 review

3% mepivacaine plain vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

3% mepivacaine plain showed no clear difference in success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review