What do systematic reviews say?

Acupressure at P6 point with thumb plus sedation vs Sham (dummy) acupressure with sedation

The review found no eligible studies for this question.

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
  0 studies
  No studies found

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)

• Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… 2019 · Cochrane All outcomes
  Reported in both trials in different ways. Forbes (TXA): mean units of replacement therapy per root extracted 617 IU (range 0 to 15,800) in 11 placebo participants versus 30 IU and 65 IU per root in 2 TXA participants…
  2 studies · 59 participants
  GRADE not reported

Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation

The review found no eligible studies for this question.

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
  0 studies
  No studies found

Acupressure at P6 point with device vs sham

It is very uncertain whether acupressure at P6 point with device changes reduction in gagging (patient-reported) compared with sham (dummy) acupressure (very low certainty).

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  RR 3.94 [1.63, 9.53]
  1 study · 34 participants
  Very low

1000 mg champignon extract vs placebo

The review found no eligible studies for this question.

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  mean 2 weeks
  Dentist-reported OLT score: listed in the Summary of findings table but no data reported. No data were reported for dentist-reported OLT score.
  0 studies
  No studies found

0.6% eucalyptus chewing gum vs Placebo chewing gum

It is very uncertain whether 0.6% eucalyptus chewing gum changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo chewing gum (very low certainty).

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  mean 4 weeks
  MD -0.1 [-0.31, 0.11]
  1 study · 65 participants
  Very low

Systemic antibiotic (oral penicillin 500 mg) plus analgesic vs Placebo plus analgesic

• Antibiotic use for irreversible pulpitis 2019 · Cochrane All outcomes

  7 days
  Corresponding risk (Antibiotics): The in between-group differences (median +/- IQR) in SPID for the penicillin group were 6.0 +/- 10.5, and for placebo 6.0 +/- 9.5. The SPPID for the penicillin group was 3.5 +/- 7.5…
  1 study · 40 participants
  Low

Ledermix root canal medicament (day 0 to 10) vs Ultracal root canal medicament (day 7 to 10)

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes

  12 months
  Tooth survival at 12 months: Not estimable (due to no events in either arm); 27 teeth in 22 patients (1 RCT). At 12 months, no teeth were lost. 1 tooth was lost at 16 months in the Ultracal group.
  1 study · 22 participants
  Very low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)

• Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… 2019 · Cochrane All outcomes
  Only reported in the Forbes (TXA) trial: over five-day follow-up, mean blood loss per participant 84.1 mL (range 4 to 323) in the placebo group (n=14) versus 61.2 mL (range 1 to 749) in the TXA group (n=14), P = 0.02.
  1 study · 28 participants
  GRADE not reported

0.6% eucalyptus chewing gum vs 0.4% eucalyptus chewing gum

0.6% eucalyptus chewing gum showed no clear difference in volatile sulphur compounds (VSC) compared with 0.4% eucalyptus chewing gum; GRADE not reported.

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  4 weeks
  MD 0.0 [-0.21, 0.21]
  1 study · 64 participants
  GRADE not reported

Pycnogenol chewing gum vs Placebo chewing gum

Pycnogenol chewing gum led to lower VSC: hydrogen sulphide compared with placebo chewing gum; GRADE not reported.

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  4 weeks
  MD -114.9 [-206.59, -23.21]
  1 study · 21 participants
  GRADE not reported

Miswak (Salvadora persica) stick vs Chlorhexidine mouthwash

It is very uncertain whether miswak (Salvadora persica) stick changes patient self-assessment VAS (scale 0 to 10) compared with chlorhexidine mouthwash (very low certainty).

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  mean 1 week
  MD -0.26 [-1.16, 0.64]
  1 study · 24 participants
  Very low

Pycnogenol chewing gum vs Placebo chewing gum

Pycnogenol chewing gum showed no clear difference in VSC: methyl mercaptan compared with placebo chewing gum; GRADE not reported.

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  4 weeks
  MD -8.4 [-24.95, 8.15]
  1 study · 21 participants
  GRADE not reported

Acupressure at P6 point with thumb vs sham

The review found no eligible studies for this question.

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
  0 studies
  No studies found

Systemic antibiotic (oral penicillin 500 mg) plus analgesic vs Placebo plus analgesic

Systemic antibiotic (oral penicillin 500 mg) plus analgesic showed no clear difference in total number of paracetamol (acetaminophen) with codeine (Tylenol)… compared with placebo plus analgesic (low certainty).

• Antibiotic use for irreversible pulpitis 2019 · Cochrane All outcomes

  7 days
  MD 2.45 [-1.23, 6.13]
  1 study · 40 participants
  Low

Pycnogenol chewing gum vs Placebo chewing gum

Pycnogenol chewing gum showed no clear difference in VSC: methyl sulphide compared with placebo chewing gum; GRADE not reported.

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  4 weeks
  MD -4.7 [-27.01, 17.61]
  1 study · 21 participants
  GRADE not reported

Acupressure at P6 point with sea band vs sham

The review found no eligible studies for this question.

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  None of the trials comparing acupressure with thumb, device or sea band to sham acupressure with or without sedation reported presence or absence of gagging.
  0 studies
  No studies found

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

It is very uncertain whether mechanical tongue cleaning (tongue scraper) changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with no tongue cleaning (very low certainty).

• Interventions for managing halitosis 2019 · Cochrane All outcomes

  mean 2 weeks
  MD -0.2 [-0.34, -0.07]
  2 studies · 46 participants
  Very low

Storage of the tooth prior to replantation (storage medium) vs Different storage medium or dry storage

The review found no eligible studies for this question.

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Acupuncture at P6 point vs sham

The review found no eligible studies for this question.

• Management of gag reflex for patients undergoing dental treatment 2019 · Cochrane All outcomes
  Presence or absence of gagging: none of the trials reported this outcome.
  0 studies
  No studies found