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Evidence found and GRADE certainty

3,032 questions · 3,358 findings · 190 reviews · related questions CL0289

No studies found 599 · 17.8%GRADE not reported 1,759 · 52.4%Very low 612 · 18.2%Low 269 · 8%Moderate 107 · 3.2%High 12 · 0.4%

Moxifloxacin + SRP vs SRP

Probing pocket depth · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review

Pre-cooling of the injection site vs Conventional treatment

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Anxiety · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Audiovisual distraction led to lower pre- and post-operative anxiety measures (Modified Child Dental… compared with conventional treatment; GRADE not reported.

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs other local anaesthetic

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Moxifloxacin + SRP vs SRP

Clinical attachment level (CAL) · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

2 findings from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at more than 1 foot from oral cavity (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) led to lower reduction in level of contamination in aerosols (CFU) at more than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether audiovisual distraction changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Cinnamon extract coolant vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): cinnamon extract coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether cinnamon extract coolant changes reduction in level of contamination in aerosols (CFU): cinnamon… compared with distilled water coolant (very low certainty).

1 finding from 1 review

Clarithromycin + SRP vs SRP

Probing pocket depth · Adults with periodontitis (chronic and aggressive)

Clarithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Swelling (mean) · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket showed no clear difference in swelling (mean) compared with no blood product (conventional); GRADE not reported.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Oral health behaviour (1-9 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in oral health behaviour (1-9 scale) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Combination system (Isolite) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in contamination of aerosols (CFU) after ultrasonic scaling / AGP · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether combination system (Isolite) changes reduction in contamination of aerosols (CFU) after ultrasonic… compared with saliva ejector (low-volume evacuator) (very low certainty).

2 findings from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review