Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
The effect of MTA versus CH in immature teeth is very uncertain (very low certainty).
1 finding from 1 review
Total mortality · Adults with oropharyngeal cancer
Surgery showed no clear difference in total mortality compared with radiotherapy alone (low certainty).
1 finding from 1 review
Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity cancer
The review found no eligible studies for this question.
1 finding from 1 review
Locoregional recurrence · Adults with oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Recurrence · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Total mortality: study reported survival significantly better with surgery and RT vs chemoradiotherapy, but no useable data; 32 participants (1 RCT, Iyer 2015 oral cavity subgroup).
1 study · 32 participants
Very low
Disease-free survival · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
1 finding from 1 review
Disease-free survival: Pandey 2018 reported 83% (superselective) vs 91% (selective) at median 36 months, not significant (P=0.69); unable to analyse (variable follow-up); 32 participants (1 RCT).
1 study · 32 participants
Very low
Pulp necrosis · Vital teeth
The pooled incidence with polyether impression material was 4.02%.
2 findings from 1 review
Proportion 4.02 [2.47, 5.92]
2985 participants
GRADE not reported
Proportion 3.17 [1.55, 5.34]
636 participants
GRADE not reported
Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
MTA increases clinical and radiographic success versus CH after direct pulp capping (moderate certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
The review found no eligible studies for this question.
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in total mortality compared with elective neck dissection (low certainty).
1 finding from 1 review
Recurrence · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Disease-free survival · Adults with oropharyngeal cancer
Surgery showed no clear difference in disease-free survival (new disease, progression, and mortality) compared with radiotherapy alone (low certainty).
1 finding from 1 review
Recurrence · Adults with oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth with mixed root development
The effect of MTA versus CH in teeth with mixed root development is very uncertain (very low certainty).
1 finding from 1 review
Pulp necrosis · Vital teeth
One study reported a 1.1% incidence with zinc polycarboxylate permanent cement.
1 finding from 1 review
Proportion 1.1
1 study
GRADE not reported
Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
The review found no eligible studies for this question.
1 finding from 1 review