Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
It is very uncertain whether systemic (oral) betamethasone changes clinical score compared with topical triamcinolone acetonide paste (very low certainty).
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Potassium permanganate versus placebo (Meidani 2018, 100 participants): no evidence of a difference in mortality; single study.
1 study · 100 participants
GRADE not reported
Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA (SEM scale, distress) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review
No numeric data reported. Study authors reported lower distress values (SEM scale) for all categories in the combined counter-stimulation and distraction group; this difference was significant when compared to the…
1 study · 78 participants
Very low
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether high-volume irrigation (~175 mL) changes wound infection compared with low-volume irrigation (~25 mL) (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
1 finding from 1 review
Patient satisfaction with actual care received (1-7 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall showed no clear difference in patient satisfaction with actual care received (1-7 scale) compared with clinical examination with 6-month recall; GRADE not reported.
1 finding from 1 review
Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Topical triamcinolone acetonide may leads to higher clinical score compared with photodynamic therapy (low certainty).
1 finding from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.10 [-0.45, 0.65]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.51, 0.71]
1 study · 21 participants
Very low
MD 0.10 [-0.43, 0.63]
1 study · 21 participants
GRADE not reported
Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Topical corticosteroid showed no clear difference in clinical score compared with placebo (low certainty).
1 finding from 1 review
Oral health behaviour (1-9 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)
Clinical examination with risk-based recall showed no clear difference in oral health behaviour (1-9 scale) compared with clinical examination with 6-month recall; GRADE not reported.
1 finding from 1 review
Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse led to lower incidence of VAP compared with saline-soaked swab; GRADE not reported.
1 finding from 1 review
Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether metronidazole + SRP changes percentage of closed pockets compared with SRP (very low certainty).
3 findings from 1 review
MD -12.20 [-29.23, 4.83]
1 study · 22 participants
Very low
MD -7.00 [-23.57, 9.57]
1 study · 22 participants
GRADE not reported
MD -2.56 [-12.33, 7.22]
2 studies · 51 participants
GRADE not reported
Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
It is very uncertain whether topical triamcinolone acetonide changes clinical resolution compared with topical tacrolimus (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Total time (examination plus treatment) (minutes) · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk)
Clinical examination with 24-month recall showed no clear difference in total time (examination plus treatment) (minutes) compared with clinical examination with 12-month recall; GRADE not reported.
2 findings from 1 review
Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal
Surgical drain (tube or gauze) led to higher maximum mouth opening (mean) compared with no drain; GRADE not reported.
1 finding from 1 review