Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Hypnosis vs Conventional treatment

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate 0.025% microspheres vs Clobetasol propionate 0.025% ointment

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.025% microspheres showed no clear difference in clinical resolution compared with clobetasol propionate 0.025% ointment; GRADE not reported.

1 finding from 1 review

Levofloxacin + SRP vs SRP

Probing pocket depth · Adults with chronic periodontitis

Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

High-volume evacuation (HVE) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 40 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).

1 finding from 1 review

Hypnosis vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether hypnosis changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Amoxicillin + metronidazole + SRP vs SRP

Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)

Amoxicillin + metronidazole + SRP led to lower percentage of closed pockets compared with SRP; GRADE not reported.

3 findings from 1 review

Clindamycin + SRP vs SRP

Probing pocket depth · Adults with aggressive periodontitis

It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with SRP (very low certainty).

3 findings from 1 review

Azithromycin + SRP vs SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).

3 findings from 1 review

Counter-stimulation and distraction (combined) vs Conventional treatment

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Drain use vs No drain

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) showed no clear difference in postoperative pain (mean) compared with no drain; GRADE not reported.

1 finding from 1 review

Ultraviolet (UV) light air decontamination vs No UV light / standard operatory

Outcome not reported · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether electrical counter-stimulation device (DentalVibe) changes self- or observational assessment of intraoperative… compared with conventional treatment (no stimulation) (very low certainty).

1 finding from 1 review