Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Endothelial function · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in endothelial function (forearm blood flow) compared with no treatment (no periodontal treatment); GRADE not reported.
1 finding from 1 review
Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether extraction of lower deciduous canines changes amount of crowding (lower incisor crowding, change) at 1-2 years compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Stability of crossbite correction (relapse of molar expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower disease-free survival, concurrent chemoradiotherapy vs radiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
HR 0.74 [0.67, 0.80]
13 studies
GRADE not reported
Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of IL-6 (pg/mL) compared with no treatment (no periodontal treatment); GRADE not reported.
3 findings from 1 review
Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
Fixed tooth-bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).
1 finding from 1 review
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with allograft plus synthetic cell-binding peptide P-15 changes changes in vertical height of alveolar ridge (mm) compared with ARP with allograft without P-15 (very low certainty).
1 finding from 1 review
Lower molars to mandible (relationship of lower back teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Lower lip bumper led to lower lower molars to mandible at 6 months compared with no active treatment (control); GRADE not reported.
1 finding from 1 review
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Surgery +/- radiotherapy + (adjuvant) chemotherapy led to lower disease-free survival, adjuvant concurrent chemoradiation vs… compared with surgery +/- radiotherapy alone (observation or adjuvant radiotherapy…; GRADE not reported.
1 finding from 1 review
HR 0.84 [0.72, 0.97]
4 studies
GRADE not reported
Harms (orthodontically-induced inflammatory root resorption) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
Time for ligation (seconds, to ligate six brackets) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Self-ligating brackets led to lower time for ligation (seconds, to ligate six brackets) compared with conventional brackets; GRADE not reported.
1 finding from 1 review
Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
Bone-borne expansion showed no clear difference in molar expansion (inter-molar distance) compared with fixed tooth-borne expansion (Hyrax) (low certainty).
1 finding from 1 review
Overall survival, adjuvant concomitant chemoradiotherapy vs post-surgery radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Surgery +/- radiotherapy + (adjuvant) chemotherapy probably leads to lower overall survival, adjuvant concurrent chemoradiation vs adjuvant… compared with surgery +/- radiotherapy alone (observation or adjuvant radiotherapy… (moderate certainty).
1 finding from 1 review
Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
Fixed bonded Hyrax appliance followed by U-bow activator therapy showed no clear difference in molar expansion compared with no treatment; GRADE not reported.
1 finding from 1 review
Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
Semi-rapid maxillary expansion showed no clear difference in canine expansion compared with rapid maxillary expansion; GRADE not reported.
1 finding from 1 review
Success rate at 1 year · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
It is very uncertain whether mineral trioxide aggregate (MTA) changes success rate at 1 year compared with root repair material (RRM) (very low certainty).
1 finding from 1 review
RR 1.00 [0.94, 1.07]
2 studies
Very low
Overall survival, induction cisplatin + 5-fluorouracil prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review