All CVD-related death · Patients with cardiovascular disease and chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Cardiovascular events · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review
All cardiovascular events (Follow-up: 6 to 25 months): One study of 303 participants assessed this outcome; however, we considered data were unreliable as participants were followed up for different lengths of time,…
1 study · 303 participants
Very low
Probing pocket depth (PPD/PD) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
Periodontal treatment (subgingival instrumentation, with or without… led to lower probing pocket depth (PPD/PD) compared with no active intervention/usual care; GRADE not reported.
1 finding from 1 review
MD -0.56 [-0.72, -0.40]
21 studies
GRADE not reported
All CVD-related death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all CVD-related death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
All‐cause death · Patients with cardiovascular disease and chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
The review found no eligible studies for this question.
1 finding from 1 review
CRP (mg/dL) at end of study · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Clinical attachment level (CAL) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
Periodontal treatment (subgingival instrumentation, with or without… led to lower clinical attachment level (CAL) compared with no active intervention/usual care; GRADE not reported.
1 finding from 1 review
MD -0.48 [-0.65, -0.31]
18 studies
GRADE not reported
Fibrinogen · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Diastolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in diastolic blood pressure (DBP, mmHg) compared with supra-gingival scaling (moderate certainty).
3 findings from 1 review
Diastolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in diastolic blood pressure (DBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).
4 findings from 1 review
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Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… led to lower clinical attachment level (CAL) compared with no treatment (no periodontal treatment); GRADE not reported.
1 finding from 1 review
Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
The review found no eligible studies for this question.
1 finding from 1 review
Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to higher endothelial function (flow-mediated dilation) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in systolic blood pressure (SBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).
4 findings from 1 review
Show 1 more finding
Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… led to lower pocket probing depth (PPD) compared with no treatment (no periodontal treatment); GRADE not reported.
1 finding from 1 review
Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of IL-6 (pg/mL) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of hs-CRP (mg/L) compared with no treatment (no periodontal treatment); GRADE not reported.
4 findings from 1 review
Show 1 more finding