What do systematic reviews say?

Sodium hypochlorite 5% vs Sodium hypochlorite 5% with proteolytic enzyme

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Sodium hypochlorite 5.25% vs Normal saline

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Sodium hypochlorite 5.25% vs Sodium hypochlorite 5.25% with hydrogen peroxide 3%

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel)

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)

The review found no eligible studies for this question.

• Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth 2008 · Cochrane All outcomes
  No eligible randomised controlled trials were identified.
  Studies not reported
  No studies found

Hand instrumentation in conjunction with (as an adjunct to) an ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal vs Hand instrumentation used alone (files and reamers used manually)

The review found no eligible studies for this question.

• Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth 2008 · Cochrane All outcomes
  No eligible randomised controlled trials were identified.
  Studies not reported
  No studies found

Conditioning and sealing with an adhesive resin (smear-removing bonding system) vs Conventional calcium hydroxide lining

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  36 months
  Whitworth 2005: 602 teeth randomised; 39 emergency recalls over the 36 months after restoration, with pulp breakdown associated with 16 teeth. The authors concluded that "dentists should be confident that pulps will be…
  1 study · 602 participants
  GRADE not reported

Glycerrhetinic acid/antibiotic mixture vs Calcium hydroxide (CH)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Prefabricated metal post and core (Category II) vs Metal custom-cast post and core (Category I)

The review found no eligible studies for this question.

• Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes

  Minimum 6 months (planned)
  No included trial compared metal-cast posts with prefabricated metal posts (a planned primary comparison); no eligible study identified.
  0 studies
  No studies found

Metal post of one alloy type vs Metal post of a different alloy type

The review found no eligible studies for this question.

• Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes

  Minimum 6 months (planned)
  No included trial evaluated alloy type in metal posts (a planned secondary comparison); no eligible study identified.
  0 studies
  No studies found

Potassium nitrate/dimethyl isosorbide/polycarboxylate cement (KNO3/DMI/PCa) vs Potassium nitrate/polycarboxylate cement (KNO3/PCa)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 9/17 in the KNO3/PCa group; symptomatic teeth required endodontic therapy or extraction.…
  1 study · 35 participants
  GRADE not reported

Cast post and core with a diaphragm vs Cast post and core without a diaphragm

The review found no eligible studies for this question.

• Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes

  Minimum 6 months (planned)
  No included trial evaluated the presence of a diaphragm in cast posts (a planned secondary comparison); no eligible study identified.
  0 studies
  No studies found

Potassium nitrate/dimethyl isosorbide/polycarboxylate cement (KNO3/DMI/PCa) vs Polycarboxylate cement (PCa) alone

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 10/12 in the PCa group. "The results in groups two and three were statistically…
  1 study · 30 participants
  GRADE not reported

Glycerrhetinic acid/antibiotic mixture vs Zinc oxide and eugenol (ZOE)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Non-metal carbon-fibre post and core (Category III; Composipost) vs Metal custom-cast post and core (Category I)

Non-metal carbon-fibre post and core (Category III; Composipost) led to lower clinical/technical failure (root fracture) compared with metal custom-cast post and core (Category I; gold alloy); GRADE not reported.

• Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes

  48 months (4 years)
  RR 0.05 [0.00, 0.90]
  1 study · 195 participants
  GRADE not reported

Potassium nitrate/polycarboxylate cement (KNO3/PCa) vs Polycarboxylate cement (PCa) alone

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Hodosh 2003 (Analysis 3.1): 9/17 in the KNO3/PCa group and 10/12 in the PCa group developed clinical symptoms requiring endodontic therapy or extraction. No significance test reported for this specific contrast; no…
  1 study · 29 participants
  GRADE not reported