Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.42 [-0.02, 0.86]
7 studies · 248 participants
Very low
MD 0.27 [-0.39, 0.93]
5 studies · 164 participants
GRADE not reported
MD 0.54 [0.18, 0.89]
3 studies · 134 participants
GRADE not reported
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in clinical attachment level (CAL) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).
3 findings from 1 review
MD 0.72 [0.43, 1.00]
17 studies · 569 participants
Very low
MD 0.47 [0.11, 0.84]
11 studies · 272 participants
GRADE not reported
MD 0.84 [0.62, 1.06]
6 studies · 192 participants
GRADE not reported
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in clinical attachment level (CAL) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review
Attachment change · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Attachment change · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.22 [0.80, 1.64]
16 studies
GRADE not reported
Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.25 [0.89, 1.61]
2 studies
GRADE not reported