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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
61 questions in 42 reviews · cluster CL0285
current versionsNo studies 36 · 59%Ungraded 15 · 24.6%Very low 6 · 9.8%Low 4 · 6.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention Cost of oral care · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis Interventions for treating oral candidiasis for patients with cancer receiving treatment (2010) · Cochrane | None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life. | 0 studies | No studies |
Any denture cleansing method (mechanical or chemical) vs Another method, sham/placebo, or no treatment Costs · Adults (over 18) wearing complete dentures (CD) or removable partial dentures (RPD) Interventions for cleaning dentures in adults (2009) · Cochrane | Noticeable absence of reports about costs of materials associated with denture cleansing methods; no included study assessed costs (Discussion; Implications for research). | 0 studies | No studies |
Bioresorbable plates or screws (or both) vs Titanium plates or screws (used as lag screws) or both Direct costs (plates, supporting equipment, hospital bed days, retreatment) · Participants over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma… · Up to 3 years postoperatively Resorbable versus titanium plates for facial fractures (2009) · Cochrane | Planned cost outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our… | 0 studies | No studies |
Prophylactic aciclovir (oral or intravenous) vs Prophylactic valaciclovir (oral) Cost of oral care · Patients being treated for cancer (predominantly haematological malignancies) Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer (2009) · Cochrane | Only one trial reported on the cost of prophylaxis for HSV (Liesveld 2002). The reported mean pharmacy costs for those randomised to receive aciclovir were $1080 compared to $320 for those initially randomised to… | 1 study · 30 participants | Ungraded |
Aciclovir (oral or intravenous) for treatment vs Placebo Cost of oral care · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients /… Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer (2009) · Cochrane | For the treatment comparison (aciclovir versus placebo), no data were available for recurrence of lesions, amount of analgesia, days of stay in hospital, cost of oral care or patient quality of life. | 0 studies | No studies |
Systemic oral acyclovir vs Placebo or no treatment Direct costs (medication, hospital bed days) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis) Acyclovir for treating primary herpetic gingivostomatitis (2008) · Cochrane | No data available in either included study. | NR | No studies |
Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Placebo or no treatment Cost of oral care · Patients with cancer receiving chemotherapy or radiotherapy or both Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane | No trial reported this planned secondary outcome for any comparison in this review | NR | No studies |
Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery) Cost/benefit (treatment time plus estimated material costs) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved… Guided tissue regeneration for periodontal infra-bony defects (2006) · Cochrane | No data were found for this outcome (listed under 'Other outcomes: No data were found for the following outcomes'). | 0 studies | No studies |
Direct resin composite veneer vs Indirect resin composite veneer Cost of treatment · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Planned outcome; cost of treatment was not reported by the included trial. | 0 studies | No studies |
Occlusal adjustment (OA) vs Placebo Cost · Adults (aged 18 years or older) with clinically diagnosed temporomandibular disorders (TMD) Occlusal adjustment for treating and preventing temporomandibular joint disorders (2003) · Cochrane | There were no data on psychosocial outcomes, costs or quality of life in any of the trials. | 0 studies | No studies |
Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO) Cost-effectiveness · Edentulous patients requiring improved denture retention Interventions for replacing missing teeth: preprosthetic surgery versus dental implants (2002) · Cochrane | Cost-effectiveness (outcome 1.9): The cost-effectiveness data could not be extracted from the report as it was combined with a separate trial. | 1 study | Ungraded |