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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
5 questions in 2 reviews · cluster CL0055
current versionsNo studies 0 · 0%Ungraded 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Low tooth brushing frequency (<2 times/day) vs High tooth brushing frequency (>=2 times/day) Early childhood caries (presence/prevalence/severity by dmft/dmfs) · Healthy children under 6 years of age (6 months to 6 years); preschool children · Leave-one-out sensitivity analysis (Alhabdan 2018 outlier excluded, k=7) Optimal tooth brushing initiation age and frequency for preventing early childhood caries: a systematic… (2025) | OR ~2.0 | 7 studies | Ungraded |
Low tooth brushing frequency (<2 times/day) vs High tooth brushing frequency (>=2 times/day) Early childhood caries (presence/prevalence/severity by dmft/dmfs) · Healthy children under 6 years of age (6 months to 6 years); preschool children · Primary analysis (all 8 studies) Optimal tooth brushing initiation age and frequency for preventing early childhood caries: a systematic… (2025) | OR 2.11 [1.25, 3.55] | 8 studies · 14981 participants | Ungraded |
Late tooth brushing initiation (>=12 months, or >=2 years in some studies) vs Early tooth brushing initiation (<12 months, or <2 years) Early childhood caries (presence/prevalence/severity by dmft/dmfs) · Healthy children under 6 years of age (6 months to 6 years); preschool children · Primary analysis (all 10 studies) Optimal tooth brushing initiation age and frequency for preventing early childhood caries: a systematic… (2025) | OR 1.40 [0.91, 2.16] | 10 studies · 23200 participants | Ungraded |
Late tooth brushing initiation (>=12 months, or >=2 years in some studies) vs Early tooth brushing initiation (<12 months, or <2 years) Early childhood caries (presence/prevalence/severity by dmft/dmfs) · Healthy children under 6 years of age (6 months to 6 years); preschool children · Leave-one-out sensitivity analysis (Wagner 2017 outlier excluded, k=9) Optimal tooth brushing initiation age and frequency for preventing early childhood caries: a systematic… (2025) | OR 1.75 [1.50, 2.03] | 9 studies | Ungraded |
Tooth brushing at least twice daily vs Brushing less than daily Mean DMFT · Children aged 5-6 years in Ajman schools · Overall Oral Health of Children and Adolescents in the United Arab Emirates: A Systematic Review of the Past Decade. (2021) | ARR 0.80 [0.64, 0.93] | 1 study · 1036 participants | Ungraded |