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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
5 questions in 3 reviews · intervention: Fluoride toothpaste/dentifrice · outcome domain: Periodontal/gingival
current versionsNo studies 0 · 0%Ungraded 1 · 20%Very low 2 · 40%Low 0 · 0%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Toothpaste with a plaque-disclosing agent vs Conventional toothpaste Gingival inflammation (short term) · Children aged 7 to 13 years with Down syndrome (mild to moderate ID); setting residential · Short term (<6 weeks) Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane | Toothpaste with a plaque-disclosing agent vs conventional toothpaste, children with Down syndrome. Ainamo & Bay Gingival Bleeding Index, mean 10 days; percent mean difference 18 (intervention) vs 8 (control), P<0.001… | 1 study · 40 participants | Very low |
1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily Gingival bleeding index (mean change from baseline) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 1.5 years Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane | MD -0.07 [-0.15, 0.01] | 1 study · 97 participants | Very low |
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan Gingival bleeding at 6 to 7 months (Gingivitis Severity Index, proportion of sites bleeding, i.e. 2 or 3 on the Loe-Silness Gingival Index) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 7 months Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane | MD -0.13 [-0.17, -0.08] | 15 studies · 1998 participants | Moderate |
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan Gingivitis at 6 to 9 months (Loe-Silness Gingival Index, 0 to 3 scale) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 9 months Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane | MD -0.27 [-0.33, -0.21] | 20 studies · 2743 participants | Moderate |
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan Gingival bleeding at 6 months (number of sites bleeding on probing or spontaneously) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 months Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane | MD 0.14 [-1.11, 1.39] | 1 study · 329 participants | Ungraded |