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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

6 questions in 1 reviews · intervention: Fluoride mouthrinse · outcome domain: Lesion arrest/remineralization

current versions
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
0.2% NaF mouthrinse + supervised toothbrushing vs Sealant
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.98 [0.84, 1.14]7 studies · 1575 participantsLow
0.2% NaF mouthrinse + supervised toothbrushing vs Sealant + 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.58 [0.43, 0.79]7 studies · 1575 participantsModerate
0.2% NaF mouthrinse + supervised toothbrushing vs 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.99 [0.84, 1.15]7 studies · 1575 participantsLow
0.2% NaF mouthrinse + supervised toothbrushing vs 1.23% APF gel
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.91 [0.68, 1.22]7 studies · 1575 participantsLow
0.2% NaF mouthrinse + supervised toothbrushing vs Resin infiltration + 5% NaF varnish
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 0.61 [0.43, 0.85]7 studies · 1575 participantsModerate
0.2% NaF mouthrinse + supervised toothbrushing vs No treatment
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019)
RR 1.94 [1.54, 2.46]7 studies · 1575 participantsModerate