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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
10 questions in 1 reviews · intervention: Fluoride gel/foam · outcome domain: Lesion arrest/remineralization
current versionsNo studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 6 · 60%Moderate 4 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
1.23% APF gel vs 10% CPP-ACP paste Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 2.19 [1.83, 2.61] | 3 studies · 4672 participants | Moderate |
1.23% APF gel vs No treatment Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 2.13 [1.79, 2.54] | 7 studies · 1575 participants | Moderate |
1.23% APF gel vs No treatment Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 2.25 [2, 2.53] | 3 studies · 4672 participants | Moderate |
1.23% APF gel vs Sealant Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 1.08 [0.82, 1.41] | 7 studies · 1575 participants | Low |
1.23% APF gel vs 5% NaF varnish Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth) · 9-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 1.05 [0.85, 1.29] | 3 studies · 4672 participants | Low |
1.23% APF gel vs 5% NaF varnish Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 1.08 [0.83, 1.4] | 7 studies · 1575 participants | Low |
1.23% APF gel vs Resin infiltration + 5% NaF varnish Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 0.67 [0.45, 0.99] | 7 studies · 1575 participants | Low |
1.23% APF gel vs Sealant + 5% NaF varnish Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth) · 8-12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 0.64 [0.44, 0.92] | 7 studies · 1575 participants | Low |
1.23% APF gel + oral health education vs Oral health education Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth) · 12 mo Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) | RR 2.47 [1.95, 3.13] | 1 study · 257 participants | Moderate |
1.23% APF gel vs 5% NaF varnish Arrest or reversal of noncavitated occlusal carious lesions · Primary and permanent teeth with noncavitated occlusal carious lesions · 8 to 12 months Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2018) | RR 1.08 [0.83, 1.40] | 7 studies | Low |