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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
555 questions in 21 reviews · intervention: Caries detection/diagnosis · outcome domain: Diagnostic accuracy
current versionsNo studies 19 · 3.4%Ungraded 489 · 88.1%Very low 17 · 3.1%Low 23 · 4.1%Moderate 7 · 1.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Radiographic caries detection vs Reference standard (often histological; also invasive opening) Advanced proximal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical) · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 95.5 [94, 97] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 38.6 [25, 54] | 14 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 9.82 [7.3, 13.3] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Negative LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Negative LR 0.54 [0.46, 0.63] | 36 studies | Ungraded |
Radiographic caries detection vs Reference standard (often histological; also invasive opening) All proximal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical) · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 90.0 [87, 92] | 38 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Negative LR for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Negative LR 0.56 [0.46, 0.68] | 12 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Negative LR for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Negative LR 0.63 [0.56, 0.72] | 38 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 80.4 [72, 87] | 11 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 43.7 [37, 51] | 50 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 89.3 [86, 92] | 44 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 95.5 [94, 97] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 2.02 [1.4, 2.9] | 11 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 64.6 [57, 71] | 94 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) PPV for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | PPV 32.1 | 11 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) NPV for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | NPV 94.3 | 36 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) PPV for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | PPV 39.5 | 36 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 84.9 [82, 89] | 55 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) PPV for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | PPV 35.6 | 51 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 89.1 [86, 92] | 38 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 44.4 [38, 51] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 39.7 [25, 56] | 11 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 5.0 [4.3, 5.8] | 55 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 44.4 [38, 51] | 22 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) NPV for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | NPV 97.5 | 55 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 75.1 [70, 81] | 55 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 12.5 [9.2, 16.9] | 50 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 50.8 [43, 59] | 36 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Sensitivity for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 40.5 [33, 48] | 34 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 92.5 [91, 94] | 31 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 77.0 [73, 81] | 51 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Negative LR for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Negative LR 0.58 [0.52, 0.65] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting advanced proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Germany Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 95.5 [94, 97] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting all (initial and advanced) proximal caries · Proximal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 5.34 [4.2, 6.8] | 31 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Specificity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 77.8 [70, 84] | 14 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Negative LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Negative LR 0.29 [0.2, 0.4] | 55 studies | Ungraded |
Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) Positive LR for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 3.46 [2.8, 4.3] | 67 studies | Ungraded |
Radiographic caries detection vs Reference standard (often histological; also invasive opening) Advanced proximal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical) · Tailored meta-analysis (Egypt) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Sensitivity 44.4 [38, 51] | 22 studies | Ungraded |
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted) NPV for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Tailored to Egypt Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | NPV 85.0 | 11 studies | Ungraded |
Radiographic caries detection vs Reference standard (often histological; also invasive opening) Advanced proximal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical) · Tailored meta-analysis (Egypt) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Positive LR 9.82 [7.3, 13.3] | 22 studies | Ungraded |
Visual caries detection vs Reference standard (often histological; also invasive opening) Advanced occlusal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical) · Conventional meta-analysis (all studies) Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) | Specificity 90.9 [88, 93] | 94 studies | Ungraded |
Fluorescence camera (FC; VistaProof) vs Reference standard (histological examination, operative intervention, or other/visual examination) Relative DOR by setting (FC, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions · More advanced (dentine/cavitated) caries lesions threshold, Laboratory using frozen teeth vs clinical (reference) Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | RDOR 2.96 [0.36, 24.45] | NR | Ungraded |
Fluorescence camera (FC) vs Reference standard Initial caries lesion detection · Primary teeth with occlusal surfaces · Initial caries lesion threshold, FC, occlusal, primary teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Sensitivity 0.482 [0.433, 0.531] | 2 studies | Ungraded |
Fluorescence camera (FC) vs Reference standard More advanced caries lesion detection · Primary teeth with occlusal surfaces · More advanced caries lesion threshold, FC, occlusal, primary teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Specificity 0.898 [0.867, 0.924] | 2 studies | Ungraded |
Fluorescence camera (FC) vs Reference standard Initial caries lesion detection · Permanent teeth with occlusal surfaces · Initial caries lesion threshold, FC, occlusal, permanent teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Sensitivity 0.708 [0.669, 0.745] | 8 studies | Ungraded |
Fluorescence camera (FC; VistaProof) vs Reference standard (histological examination, operative intervention, or other/visual examination) Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Primary teeth, occlusal surfaces, with suspected caries lesions · More advanced (dentine/cavitated) caries lesions threshold Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 7); pooled DOR highest for FC among the three methods. Heterogeneity I2=80%. Numeric pooled values not available in the… | NR | Ungraded |
Fluorescence camera (FC) vs Reference standard More advanced caries lesion detection · Permanent teeth with occlusal surfaces · More advanced caries lesion threshold, FC, occlusal, permanent teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Specificity 0.669 [0.627, 0.708] | 8 studies | Ungraded |
Fluorescence camera (FC; VistaProof) vs Reference standard (histological examination, operative intervention, or other/visual examination) Relative DOR by setting (FC, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions · More advanced (dentine/cavitated) caries lesions threshold, Laboratory vs clinical (reference) Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | RDOR 3.83 [0.53, 27.73] | NR | Ungraded |
Fluorescence camera (FC) vs Reference standard Initial caries lesion detection · Permanent teeth with occlusal surfaces · Initial caries lesion threshold, FC, occlusal, permanent teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Specificity 0.821 [0.739, 0.885] | 8 studies | Ungraded |
Fluorescence camera (FC; VistaProof) vs Reference standard (histological examination, operative intervention, or other/visual examination) Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Permanent teeth, occlusal surfaces, with suspected caries lesions · Initial caries lesions threshold Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 6); accuracy similar among the three methods (very low inconsistency). Heterogeneity I2=0%. Numeric pooled values not… | NR | Ungraded |
Fluorescence camera (FC) vs Reference standard Initial caries lesion detection · Primary teeth with occlusal surfaces · Initial caries lesion threshold, FC, occlusal, primary teeth Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) | Specificity 0.815 [0.713, 0.892] | 2 studies | Ungraded |