Transvaginal permanent mesh probably leads to lower awareness of prolapse (0.5 to 7 years) compared with native tissue repair (moderate certainty).
Transvaginal biological graft showed no clear difference in surgery for recurrent prolapse (1 to 2 years) compared with native tissue repair (moderate certainty).
Transvaginal biological graft showed no clear difference in recurrent prolapse on examination compared with native tissue repair (low certainty).
Transvaginal biological graft showed no clear difference in visceral injury compared with native tissue repair (low certainty).
It is very uncertain whether transvaginal biological graft changes bladder function compared with native tissue repair (very low certainty).
Transvaginal biological graft showed no clear difference in painful intercourse ‐ de novo dyspareunia compared with native tissue repair (moderate certainty).
It is very uncertain whether transvaginal biological graft changes quality of life compared with native tissue repair (very low certainty).
Transvaginal permanent mesh may leads to higher repeat surgery (0.5 to 7 years) compared with native tissue repair (low certainty).
It is very uncertain whether transvaginal permanent mesh changes recurrent prolapse on examination (any compartment) compared with native tissue repair (very low certainty).
Transvaginal permanent mesh may leads to higher visceral injury compared with native tissue repair (low certainty).
Transvaginal permanent mesh probably leads to higher mesh exposure compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh probably leads to higher bladder function compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh showed no clear difference in painful intercourse ‐ de novo dyspareunia compared with native tissue repair (moderate certainty).
It is very uncertain whether transvaginal permanent mesh changes quality of life compared with native tissue repair (very low certainty).
Transvaginal biological graft showed no clear difference in awareness of prolapse (1 to 3 years) compared with native tissue repair (moderate certainty).
Anticholinergics showed no clear difference in mean change from baseline in condition‐specific quality of lifeScale… compared with placebo (low certainty).
Anticholinergics probably leads to higher patient perception of cure or improvement compared with placebo (moderate certainty).
Anticholinergics showed no clear difference in mean number of urgency episodes per 24 hours compared with placebo (moderate certainty).
Anticholinergics may leads to higher adverse events: dry mouth compared with placebo (low certainty).
Anticholinergics may leads to higher adverse events:urinary retention compared with placebo (low certainty).