Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,234 questions · 2,325 findings · 216 reviews · Airways

No studies found 249 · 10.7%GRADE not reported 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Intervention not reported

Asthma symptoms measured using various techniques. · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

Quality of life Measured using various scales. · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

Exercise tolerance Measured using 6MWD · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

PEFR L/min · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

VEmax · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

VOmax · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

HRmax bpm · patients with asthma aged eight years or older
1 finding from 1 review

MHRV vs placebo

Change in Morning PEF after 12 months (% predicted) · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in change in Morning PEF after 12 months (% predicted) compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

Change in Evening PEF after 12 months (% predicted) · asthmatics with sensitivity to house dust mite

MHRV probably leads to higher change in Evening PEF after 12 months (% predicted) compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

FEV1 · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in change in FEV1 after 12 months (% predicted) compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in quality of life SGRQ Scale from 0 to 100 (0 on the scale is better) compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

Mean exacerbations requiring a course of oral corticosteroids · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in exacerbations needing oral steroids compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

Exacerbations leading to ED visits · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in exacerbations needing ED visit compared with placebo (moderate certainty).

1 finding from 1 review

MHRV vs placebo

Exacerbations needing hospitalisation · asthmatics with sensitivity to house dust mite

MHRV showed no clear difference in exacerbations needing hospitalisation compared with placebo (moderate certainty).

1 finding from 1 review