Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Intraventricular haemorrhage, Papile grade 3/4 · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes intraventricular haemorrhage grade III or IV compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Patent ductus arteriosus · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes patent ductus arteriosus compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Oxygen requirement at 36 weeks' postmenstrual age · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes chronic lung disease (oxygen supplementation at 36 weeks'… compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Proven necrotising enterocolitis (Bell's stage II or III) · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes proven necrotising enterocolitis (Bell's stage II or III) compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Retinopathy of prematurity, any or severe (stage ≥ III) · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes retinopathy of prematurity, any or severe (stage ≥ III) compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Intervention not reported

First intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in first intubation attempt success rate (outcome achieved at time of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Weight < 1000 g (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in weight < 1000 g (outcome achieved at time of intubation attempt and… (moderate certainty).

1 finding from 1 review

Intervention not reported

Professional category of the intubator ‐ fellow: first intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in professional category of the intubator ‐ fellow: first intubation… (low certainty).

1 finding from 1 review

Intervention not reported

Professional category of the intubator ‐ resident: first intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in professional category of the intubator ‐ resident: first intubation… (moderate certainty).

1 finding from 1 review

Intervention not reported

Premedication given ‐ no premedication given: first intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in premedication given ‐ no premedication given: first intubation… (moderate certainty).

1 finding from 1 review

Intervention not reported

Timing of intubation ‐ just after birth in the delivery room: first intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in timing of intubation ‐ just after birth in the delivery room: first… (moderate certainty).

1 finding from 1 review

Intervention not reported

Timing of intubation ‐ following admission to NICU: first intubation attempt success rate (outcome achieved at time of intubation attempt and not followed up) · neonates requiring endotracheal intubation

The intervention showed no clear difference in timing of intubation ‐ following admission to NICU: first intubation… (moderate certainty).

1 finding from 1 review