Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Dose comparison: oestrogen 100 µg patch vs 200 µg patch plus progestogen

Withdrawals due to adverse events · women with PMS

It is very uncertain whether dose comparison: oestrogen 100 µg patch changes adverse events ‐ withdrawal rates over 8 months' compared with 200 µg patch plus progestogen (very low certainty).

1 finding from 1 review

Dose comparison: oestrogen 100 µg patch vs 200 µg patch plus progestogen

Adverse events ‐ specific side effects attributed to oestrogen over 8 months' · women with PMS

It is very uncertain whether dose comparison: oestrogen 100 µg patch changes adverse events ‐ specific side effects attributed to oestrogen over… compared with 200 µg patch plus progestogen (very low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Live birth · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

It is very uncertain whether any anti‐adhesion therapy changes live birth a compared with placebo or no treatment following operative hysteroscopy (very low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

Any anti‐adhesion therapy may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy… compared with placebo or no treatment following operative hysteroscopy (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs anti‐adhesion therapy B following operative hysteroscopy

Live birth · women treated by operative hysteroscopy for uterine pathology

Any anti‐adhesion therapy A showed no clear difference in live birth a compared with anti‐adhesion therapy B following operative hysteroscopy (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs anti‐adhesion therapy B following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology

Any anti‐adhesion therapy A may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy (6‐12… compared with anti‐adhesion therapy B following operative hysteroscopy (low certainty).

1 finding from 1 review