Overall survival · children and young adults with diffuse brainstem glioma
Hyperfractionated radiotherapy showed no clear difference in overall survival compared with conventional radiotherapy (low certainty).
1 finding from 1 review
Event‐free survival · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neurological response · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Radiological response · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Toxicities · children and young adults with diffuse brainstem glioma
1 finding from 1 review
Progression‐free survival · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Event‐free survival · children and young adults with diffuse brainstem glioma
Hyperfractionated radiotherapy showed no clear difference in event‐free survival compared with conventional radiotherapy (low certainty).
1 finding from 1 review
Quality of life · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neurological response · children and young adults with diffuse brainstem glioma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Radiological response defined as the number of participants with a reduction in tumour size > 50% · children and young adults with diffuse brainstem glioma
It is very uncertain whether hyperfractionated radiotherapy changes radiological response defined as the number of participants with a… compared with conventional radiotherapy (very low certainty).
1 finding from 1 review
Toxicities · children and young adults with diffuse brainstem glioma
1 finding from 1 review
Overall survival · children and young adults with diffuse brainstem glioma
Hypofractionated radiotherapy showed no clear difference in overall survival compared with conventional radiotherapy (moderate certainty).
1 finding from 1 review
Progression‐free survival · children and young adults with diffuse brainstem glioma
Hypofractionated radiotherapy showed no clear difference in progression‐free survival compared with conventional radiotherapy (low certainty).
1 finding from 1 review
Complete response · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in complete response compared with standard induction therapies (low certainty).
1 finding from 1 review
Early toxicities (during preoperative chemotherapy): febrile neutropenia (2 or more episodes), proven fungal infections, septicemia (1 or more episodes), gastrointestinal toxicity (grade 3 or 4), renal toxicity (glomerular filtration rate < 80 ml/... · patients with high‐risk neuroblastoma
1 finding from 1 review
Treatment‐related mortality · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in treatment‐related mortality compared with standard induction therapies (low certainty).
1 finding from 1 review
Overall survival · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in overall survival compared with standard induction therapies (low certainty).
1 finding from 1 review
Progression‐free survival ‐ not reported · patients with high‐risk neuroblastoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Event‐free survival · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in event‐free survival compared with standard induction therapies (low certainty).
1 finding from 1 review